2,2,3-Trifluoro-succinic acid CAS 664-66-4
| CAS No. | 664-66-4 |
| Molecular Formula | C4H3F3O4 |
| Molecular Weight | 172.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,2,3-Trifluoro-succinic acid is closely related to a carbohydrate-derived structure, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,2,3-Trifluoro-succinic acid (CAS 664-66-4), molecular formula C4H3F3O4 and molecular weight 172.06 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carbohydrate-derived structure, fluorine substitution, 2,2,3-Trifluoro-succinic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 172.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,2,3-Trifluoro-succinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H3F3O4 |
| Molecular Weight | 172.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- 5,5,5-Trifluoro-4-hydroxypentanoic acid (CAS 1216314-45-2)
- 4,4,4-Trifluoro-3-methoxybutanoic acid (CAS 1343115-14-9)
- 5,5,5-Trifluoro-2-hydroxypentanoic acid (CAS 1485492-68-9)
- Methyl 4,4,4-trifluoro-2-hydroxybutanoate (CAS 1610538-11-8)
- 3,3,3-Trifluoro-2-methoxy-2-methylpropanoic acid (CAS 56135-02-5)
- 4,4,4-Trifluoro-3-hydroxy-3-methylbutanoic acid (CAS 338-03-4)
- Ethyl 3,3,3-trifluoro-DL-lactate (CAS 94726-00-8)
- Methyl 2,3,3-trifluoro-3-methoxypropanoate (CAS 758-69-0)
Recommended Standards
- 2-(2,2,2-Trifluoroacetoxy)acetic acid (CAS 78517-61-0)
- Nonan-2-ylboronic acid (CAS 3088-78-6)
- Glyphosate-13C2,15N (CAS 1185107-63-4)
- rel-(2R,3R)-Butanedioic acid, 2,3-dihydroxy-, sodium salt (1:1) (CAS 60131-40-0)
- 4-CHloro-2-(2-methylpropoxy)benzonitrile (CAS 1342668-76-1)
- 2-(Trifluoroacetyl)cyclopentan-1-one (CAS 361-73-9)
- N-((5-(3-Methoxyphenyl)-1H-1,2,4-triazol-3-yl)methyl)-4-methylaniline (CAS 1171933-87-1)
- 4-Methyl-5,6-dihydro-2H-pyran-2-one (CAS 2381-87-5)
- Methyl 2-(4-acetyl-2-iodophenyl)acetate (CAS 1234562-69-6)
- 2-((3,4-Dimethyl-2-oxo-2h-chromen-7-yl)oxy)acetic acid (CAS 35679-93-7)
- 2-Isopropylthiazole-5-carboxylic Acid (CAS 62657-87-8)
- Dimethyl 2-methylenemalonate (CAS 3377-21-7)
- 2-((4-Chlorobenzyl)oxy)-3-ethoxybenzaldehyde (CAS 1094657-48-3)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
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