7-(Chlorosulfonyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid CAS 66410-36-4
| CAS No. | 66410-36-4 |
| Molecular Formula | C9H7ClO6S |
| Molecular Weight | 278.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-(Chlorosulfonyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid (CAS 66410-36-4), molecular formula C9H7ClO6S and molecular weight 278.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 7-(Chlorosulfonyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7ClO6S |
| Molecular Weight | 278.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorosulfonyl Standards
- 3-[4-(chlorosulfonyl)-2-methylphenoxy]propanoic acid (CAS 1016822-12-0)
- methyl 3-(chlorosulfonyl)-4-(methoxymethyl)benzoate (CAS 1154149-38-8)
- methyl 3-(chlorosulfonyl)-5-(methoxymethyl)benzoate (CAS 1154149-63-9)
- 2-[3-(chlorosulfonyl)-2,6-dimethylphenoxy]acetic acid (CAS 1240528-80-6)
- methyl 2-[2-(chlorosulfonyl)-5-methoxyphenyl]acetate (CAS 18944-99-5)
- 5-(Chlorosulfonyl)-2-propxybenzoic acid (CAS 215299-78-8)
- Ethyl 3-(chlorosulfonyl)-4-methoxybenzoate (CAS 262589-79-7)
- Methyl 2-(4-(chlorosulfonyl)-2-methylphenoxy)acetate (CAS 56077-82-8)
Recommended Standards
- 5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonyl chloride (CAS 98165-58-3)
- Ethyl 2-(4-chloro-5-cyclopropyl-3-(difluoromethyl)-1h-pyrazol-1-yl)acetate (CAS 1002033-85-3)
- 2-chloro-4-[({[(2-fluorophenyl)methylene]amino}oxy)carbonyl]pyridine (CAS 680215-44-5)
- 1-(4-Chlorophenyl)-3-(2,6-difluorophenyl)prop-2-en-1-one (CAS 1095396-00-1)
- tert-Butyl (S)-(1-(2-chloroacetyl)pyrrolidin-3-yl)carbamate (CAS 1354015-96-5)
- (R)-Benzyl (1-(2-aminoethyl)pyrrolidin-3-yl)carbamate (CAS 1354016-29-7)
- 2-Chloro-n-[(2-chloro-6-fluorophenyl)methyl]-n-methylpropanamide (CAS 1154151-13-9)
- 4-Chloro-N-(4-(2-(furan-2-ylmethylene)hydrazinecarbonyl)phenyl)benzenesulfonamide (CAS 477733-05-4)
- 2-Bromo-1-(chloromethyl)-4-methylbenzene (CAS 147542-02-7)
- (Z)-N'-Hydroxybenzimidamide (CAS 69289-27-6)
- Ethyl 7-(bis(tert-butoxycarbonyl)amino)-5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 2271471-16-8)
- Methylenediurea (CAS 13547-17-6)
- 3-Methyl-1H-cycloocta[c]pyrazole (CAS 110661-74-0)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
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