2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one CAS 66427-86-9
| CAS No. | 66427-86-9 |
| Molecular Formula | C12H9ClN4O |
| Molecular Weight | 260.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one (CAS 66427-86-9) is a high-purity analytical reference standard with the molecular formula C12H9ClN4O and a molecular weight of 260.68 g/mol.
2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one (C12H9ClN4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN4O |
| Molecular Weight | 260.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 1-(pyridin-2-ylmethyl)piperidine-4-carboxylic acid (CAS 193538-28-2)
- 3-(2-Chlorophenyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine (CAS 618092-80-1)
- 3-{2-[(4-Methylbenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1220018-14-3)
- (Mercaptomethyl)diphenylphosphineoxide (CAS 324753-14-2)
- 1-(4-Hydroxy-3-(((4-methyl-4h-1,2,4-triazol-3-yl)thio)methyl)phenyl)ethan-1-one (CAS 730997-82-7)
- 2-Bromo-5-(3-methoxypropylsulfonyl)thiophene (CAS 1379334-94-7)
- (5-Methyl-2-oxazolyl)methanamine (CAS 1017228-56-6)
- 1-(3-Fluorophenyl)-2-(1h-imidazol-1-yl)ethan-1-one (CAS 630403-99-5)
- Cabotegravir Impurity 15 (CAS CATO-C4X-287615)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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