2-Cyclopropyl-1-(3-(trifluoromethyl)phenyl)quinazolin-4(1H)-one CAS 66491-86-9
| CAS No. | 66491-86-9 |
| Molecular Formula | C18H13F3N2O |
| Molecular Weight | 330.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Cyclopropyl-1-(3-(trifluoromethyl)phenyl)quinazolin-4(1H)-one (CAS 66491-86-9), molecular formula C18H13F3N2O and molecular weight 330.30 g/mol, is a CATO reference standard with documented purity and traceability.
2-Cyclopropyl-1-(3-(trifluoromethyl)phenyl)quinazolin-4(1H)-one (C18H13F3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Cyclopropyl-1-(3-(trifluoromethyl)phenyl)quinazolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13F3N2O |
| Molecular Weight | 330.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-amino-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]acetamide (CAS 444289-11-6)
- 5-((4-Fluorophenoxy)methyl)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole (CAS 478031-78-6)
- 2-{[3-(Trifluoromethyl)benzyl]oxy}-1-naphthaldehyde (CAS 866133-96-2)
- 5-Phenyl-6-(p-tolyl)-2-(trifluoromethyl)pyrimidin-4(1H)-one (CAS 651316-08-4)
- 1-Phenyl-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 31788-83-7)
- (Z)-N'-[(2,4-Dichlorophenyl)methoxy]pyridine-2-carboximidamide (CAS 338753-69-8)
- Pyridin-3-yl(pyridin-4-yl)methanone (CAS 56970-93-5)
- 1-[4-(4-chloro-but-2-ynyloxy)-phenyl]-ethanone (CAS 1284229-49-7)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
- (Z)-[2-(4-Chlorobenzenesulfonyl)-1-phenylethylidene][(4-chlorophenyl)methoxy]amine (CAS 338794-61-9)
- 3-Bromo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (CAS 1263378-90-0)
- 4-Amino-1,2,5-oxadiazole-3-carboxamide (CAS 13300-88-4)
- N- (1-Deoxy- D- fructos- 1- yl) -L- cysteine (CAS 846568-65-8)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
Why CATO?
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