6-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine CAS 66521-83-3
| CAS No. | 66521-83-3 |
| Molecular Formula | C8H11N3 |
| Molecular Weight | 149.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 66521-83-3), molecular formula C8H11N3 and molecular weight 149.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (C8H11N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H11N3 |
| Molecular Weight | 149.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
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- alpha-Chloro-3-fluorobenzaldoxime (CAS 58606-42-1)
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- 1,1-Difluoropropan-2-amine hydrochloride (CAS 1384427-90-0)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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