[4-(2-methyl-1,3-dioxolan-2-yl)phenyl]methanamine CAS 66522-61-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [4-(2-methyl-1,3-dioxolan-2-yl)phenyl]methanamine.

CATO supplies [4-(2-methyl-1,3-dioxolan-2-yl)phenyl]methanamine (CAS 66522-61-0), a certified reference material (molecular formula C11H15NO2, MW 193.24 g/mol) for analytical method development and quality control.

[4-(2-methyl-1,3-dioxolan-2-yl)phenyl]methanamine (C11H15NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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