Dyclonine Impurity 2 CAS 66536-15-0
| CAS No. | 66536-15-0 |
| Molecular Formula | C13H16O2 |
| Molecular Weight | 204.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Dyclonine Impurity 2 (CAS 66536-15-0) is a certified pharmaceutical impurity reference standard with the molecular formula C13H16O2 and a molecular weight of 204.26 g/mol.
The molecular framework of Dyclonine Impurity 2 (C13H16O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H16O2 |
| Molecular Weight | 204.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
Related Dyclonine Standards
- Dyclonine Impurity 19 (CAS CATO-C4X-188119)
- Dyclonine Impurity 12 (CAS 91763-92-7)
- Dyclonine Impurity 29 (CAS 55168-27-9)
- Dyclonine Impurity 31 (CAS 1042521-37-8)
- Dyclonine Impurity 32 (CAS 35922-84-0)
- Dyclonine Impurity N6 (CAS 50743-14-1)
- Dyclonine Impurity N8 (CAS 61405-66-1)
- Dyclonine Impurity 5 (CAS 165261-15-4)
Recommended Standards
- Ozagrel Impurity 5 (CAS CATO-C4X-19715)
- Butylphthalide Impurity 11 (CAS 111943-62-5)
- Diethylene Glycol Monobutyl Ether Acetate (CAS 124-17-4)
- Warfarin Impurity 11 (CAS CATO-C4X-178111)
- Atenolol impurity 27 (CAS CATO-C4X-154927)
- Ceftolozane Impurity 26 (CAS CATO-C4X-240626)
- Felodipine Impurity 37 (CAS CATO-C4X-109437)
- 9-Hydroxy Benzopyrene (CAS 17573-21-6)
- (2Z)-2-[(Dimethylamino)methylidene]-7-fluoro-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 339010-46-7)
- tert-Butyl 2-(((5-methylpyridin-2-yl)thio)methyl)piperidine-1-carboxylate (CAS 1353979-11-9)
- S-Allyl methylcarbamothioate (CAS 62604-10-8)
- 1-(Piperidin-4-yl)azetidin-3-ol hydrochloride (CAS 1443624-48-3)
- 2-Chloro-6-methylquinoline-3-carbonitrile 483287-37-2 6609AB C11H7ClN2 (CAS 483287-37-2)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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