3-Methyl-6-(3-nitrophenyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 66548-74-1
| CAS No. | 66548-74-1 |
| Molecular Formula | C12H9N5O2 |
| Molecular Weight | 255.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Methyl-6-(3-nitrophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 66548-74-1), molecular formula C12H9N5O2 and molecular weight 255.23 g/mol, is a CATO reference standard with documented purity and traceability.
3-Methyl-6-(3-nitrophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (C12H9N5O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-Methyl-6-(3-nitrophenyl)-[1,2,4]triazolo[4,3-b]pyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9N5O2 |
| Molecular Weight | 255.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 5 |
Related Methyl Standards
- 3-(4-Nitrophenyl)imidazo[1,2-a]pyridin-2-ol (CAS 102862-21-5)
- 6-(3-Nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 1039365-30-4)
- 1-(4-Nitrophenyl)-2-phenylethane-1,2-dione (CAS 22711-24-6)
- 6-(4-Nitrophenyl)pyrrolo[1,2-a]pyrazin-8-ol (CAS 2034157-30-5)
- 7-Methyl-2-(4-nitrophenyl)-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 832144-06-6)
- 2-(4-Nitrophenyl)-1-phenylpropan-1-one (CAS 105590-46-3)
- (1E)-1-(4-nitrophenyl)ethanone phenylhydrazone (CAS 77635-72-4)
- 3-(2-Nitrophenyl)-2-thioxothiazolidin-4-one (CAS 52494-41-4)
Recommended Standards
- 3-Amino-1,2-dihydroxyanthracene-9,10-dione (CAS 3963-78-8)
- 3-Methyl-6-(pyridin-4-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 954262-12-5)
- 3-Azido-2,3-dideoxyuridine (CAS 84472-85-5)
- 3-methyl-6-pyridin-3-ylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 953745-07-8)
- Ethyl 1,3-dimethyl-1H-indole-2-carboxylate (CAS 61838-90-2)
- tert-Butyl [(1S)-1-(hydrazinocarbonyl)-3-(methylthio)propyl]carbamate (CAS 49759-74-2)
- 5-Imino-4-methyl-2,5-dihydro-1h-pyrazol-3-amine (CAS 1284219-41-5)
- N-isopropylthiophene-3-carboxamide (CAS 531549-10-7)
- 1-(4-Chlorophenyl)-2-[(5-iodo-2,6-dimethylpyrimidin-4-yl)oxy]ethan-1-one (CAS 477871-93-5)
- N-(2-Amino-5-hydroxy-6-methylpyrimidin-4-yl)-4-methylbenzamide (CAS 61581-42-8)
- (1-cyclobutylcyclobutyl)methanamine hydrochloride (CAS 1909326-44-8)
- Methyl (S)-4-(Boc-amino)-5-hydroxypentanoate (CAS 126587-35-7)
- 2-(2,6-Dichloropyridin-4-yl)-5-(isoxazol-5-yl)-1,3,4-oxadiazole (CAS 680214-03-3)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com