3-Chloro-6-(3-fluorophenyl)pyridazine CAS 66573-61-3
| CAS No. | 66573-61-3 |
| Molecular Formula | C10H6ClFN2 |
| Molecular Weight | 208.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chloro-6-(3-fluorophenyl)pyridazine (C10H6ClFN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Chloro-6-(3-fluorophenyl)pyridazine (CAS 66573-61-3) is a high-purity analytical reference standard with the molecular formula C10H6ClFN2 and a molecular weight of 208.62 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-6-(3-fluorophenyl)pyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClFN2 |
| Molecular Weight | 208.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-3-(4-fluorophenyl)pyrazine (CAS 1094461-27-4)
- 2-Chloro-5-(4-fluorophenyl)pyrazine (CAS 115104-61-5)
- 5-Chloro-2-fluoro-3-(pyridin-4-yl)pyridine (CAS 1214337-85-5)
- 2-Chloro-5-fluoro-3,4'-bipyridine (CAS 1214343-30-2)
- 6-Chloro-5-fluoro-3,4'-bipyridine (CAS 1214366-80-9)
- 6-Chloro-5-fluoro-3,3'-bipyridine (CAS 1214371-22-8)
- 2-Chloro-5-fluoro-3,3'-bipyridine (CAS 1214382-27-0)
- 2-Chloro-4-(2-fluorophenyl)pyrimidine (CAS 1227570-74-2)
Recommended Standards
- 3-Chloro-6-(2-fluorophenyl)pyridazine (CAS 66549-06-2)
- 3-Chloro-6-(4-fluorophenyl)pyridazine (CAS 66548-52-5)
- 2-Chloro-5-(4-fluorophenyl)pyrimidine (CAS 75175-39-2)
- 4-Chloro-2-(3-fluorophenyl)pyrimidine (CAS 76128-70-6)
- 2-Amino-4-(6-nitrobenzo[d][1,3]dioxol-5-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 315245-17-1)
- (2r,3r)-3,4-Diaminobutan-2-ol (CAS 1335234-12-2)
- 2,2'-((1E,1'E)-(((1R,2S)-1,2-Bis(4-methoxyphenyl)ethane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))diphenol (CAS 58546-78-4)
- 1-(3,4-Dichlorobenzyl)-3-(3-((2,4-dichlorobenzyl)oxy)phenyl)-1H-pyrazole (CAS 477712-78-0)
- 2-(2,4-Difluorophenoxy)-2-methylpropanoic acid (CAS 667413-00-5)
- 3-(3-Chlorophenyl)-1H-indazol-5-amine (CAS 1175640-23-9)
- [1-(3-Fluoro-4-methylphenyl)-1H-1,2,3-triazol-4-yl]methanol (CAS 1250228-33-1)
- 2-Amino-2-(tetrahydro-2H-thiopyran-4-yl)ethan-1-ol (CAS 898796-22-0)
- 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester (CAS 868536-53-2)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com