2-Bromo-N-(pyridin-2-yl)acetamide CAS 66642-53-3

Purity 97%+In StockPharmaceutical Standards
CAS No.66642-53-3
Molecular FormulaC7H7BrN2O
Molecular Weight215.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-N-(pyridin-2-yl)acetamide CAS 66642-53-3 chemical structure

Description

The occurrence of 2-Bromo-N-(pyridin-2-yl)acetamide is closely related to an amide group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Bromo-N-(pyridin-2-yl)acetamide (CAS 66642-53-3) is a high-purity analytical reference standard with the molecular formula C7H7BrN2O and a molecular weight of 215.05 g/mol.

The molecular framework of 2-Bromo-N-(pyridin-2-yl)acetamide (C7H7BrN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H7BrN2O
Molecular Weight215.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Halogen ContentBr-containing
Nitrogen Atoms2

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