9-Benzyl-6-chloro-N-phenyl-9H-purin-2-amine CAS 666823-27-4
| CAS No. | 666823-27-4 |
| Molecular Formula | C18H14ClN5 |
| Molecular Weight | 335.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
9-Benzyl-6-chloro-N-phenyl-9H-purin-2-amine (CAS 666823-27-4) is a high-purity analytical reference standard with the molecular formula C18H14ClN5 and a molecular weight of 335.79 g/mol.
The molecular framework of 9-Benzyl-6-chloro-N-phenyl-9H-purin-2-amine (C18H14ClN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 9-Benzyl-6-chloro-N-phenyl-9H-purin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14ClN5 |
| Molecular Weight | 335.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Benzyl Standards
- 9-Benzyl-2-chloro-N-phenyl-9H-purin-6-amine hydrochloride (CAS 125802-43-9)
- 1-(3-Chloro-2,5-dimethoxyphenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 1306738-43-1)
- 8-Chloro-2-(2-(quinolin-2-yl)ethyl)phthalazin-1(2H)-one (CAS 1433204-04-6)
- 3-(1-Benzyl-5-chloro-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 860649-49-6)
- 3-Chloro-n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)quinoxalin-2-amine (CAS 376364-59-9)
- 4-Chloro-6-(4-methoxyphenyl)-2-(3-methylphenyl)pyrimidine-5-carbonitrile (CAS 477859-03-3)
- 4-Chloro-7-(4-methoxy-phenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 220835-25-6)
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Recommended Standards
- 7-Chloro-2-(3-methoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine (CAS 889939-49-5)
- N-((3-(4-chlorophenyl)isoxazol-5-yl)methyl)-2-morpholinoacetamide (CAS 478043-47-9)
- 7-(3-Chloro-4-methylphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol (CAS 865546-59-4)
- N-(1-Chloro-4-methyl-5H-pyrido[4,3-b]indol-8-yl)benzamide (CAS 915778-07-3)
- (-)-Diacetyl-D-tartaric anhydride (CAS 70728-23-3)
- 4-Iodo-6-(trifluoromethyl)pyridin-2-amine (CAS 1227581-86-3)
- N2,N3,1,4-tetraphenylbutane-2,3-diamine (CAS 126503-85-3)
- (2-Fluoro-1,3-thiazol-4-yl)methanol (CAS 153027-87-3)
- 1-(2-Amino-6-methylphenyl)piperidin-2-one (CAS 1211496-23-9)
- 7-(Hydroxymethyl)-5-methylquinolin-8-ol (CAS 77249-82-2)
- 3,5-Dichlorophenethyl acetate (CAS 85263-21-4)
- 1-(5-Methoxy-2-methylphenyl)ethan-1-one (CAS 110743-57-2)
- N-(2-((4-bromophenyl)thio)ethyl)benzamide (CAS 338955-66-1)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
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