Bisoprolol Impurity 111 CAS 66722-65-4
| CAS No. | 66722-65-4 |
| Molecular Formula | C20H33NO5 |
| Molecular Weight | 367.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Bisoprolol Impurity 111 (CAS 66722-65-4, C20H33NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H33NO5, Bisoprolol Impurity 111 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Bisoprolol Impurity 111 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H33NO5 |
| Molecular Weight | 367.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 1 |
Related Bisoprolol Standards
- Bisoprolol Impurity 84 (CAS CATO-C4X-124784)
- Bisoprolol Impurity 66 (CAS CATO-C4X-124766)
- Bisoprolol Impurity 89 (CAS 2417155-12-3)
- Bisoprolol Impurity 118 (CAS 2919749-44-1)
- Bisoprolol EP Impurity G (CAS 1215342-36-1)
- Bisoprolol Impurity 22 (CAS 1447715-45-8)
- Bisoprolol Impurity 109 (CAS 87844-84-6)
- Bisoprolol Impurity 65 (CAS CATO-C4X-124765)
Recommended Standards
- Alvimopan Impurity 4 (CAS 156130-41-5)
- Perindopril Impurity 37 (CAS CATO-C4X-125237)
- Alvimopan impurity 14 (CAS CATO-C4X-114514)
- Venlafaxine impurity 56 (CAS 916918-81-5)
- Dalilesen Impurity 16 (CAS CATO-C4X-301016)
- Ornidazole impurity 32 (CAS 1826157-12-3)
- Piracetam impurity 42 (CAS CATO-C4X-123542)
- 5-Dodecyl-6-methylpyrimidin-4(3H)-one (CAS 103980-61-6)
- Rasagiline Impurity 40 (CAS 702640-45-7)
- 1-(2-Amino-6-methylphenyl)ethanone hydrochloride (CAS 90943-28-5)
- 4,6-Dichloro-2-(p-tolyl)pyrimidine (CAS 21139-61-7)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine (CAS 1311279-54-5)
- 2-({5-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]pyrimidin-2-yl}sulfanyl)-1-(4-chlorophenyl)ethan-1-one (CAS 344263-13-4)
- Liraglutide (CAS 204656-20-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com