4-((Tetrahydro-2H-pyran-2-yl)oxy)but-2-ynal CAS 66725-78-8

Purity 97%+In StockPharmaceutical Standards
CAS No.66725-78-8
Molecular FormulaC9H12O3
Molecular Weight168.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-((Tetrahydro-2H-pyran-2-yl)oxy)but-2-ynal CAS 66725-78-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 168.19 g/mol gives 4-((Tetrahydro-2H-pyran-2-yl)oxy)but-2-ynal distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-((Tetrahydro-2H-pyran-2-yl)oxy)but-2-ynal (CAS 66725-78-8), molecular formula C9H12O3 and molecular weight 168.19 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-((Tetrahydro-2H-pyran-2-yl)oxy)but-2-ynal (C9H12O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H12O3
Molecular Weight168.19 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976

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