5,2'-Dihydroxyflavone CAS 6674-39-1
| CAS No. | 6674-39-1 |
| Molecular Formula | C11H6Cl6O4 |
| Molecular Weight | 414.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5,2'-Dihydroxyflavone (C11H6Cl6O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5,2'-Dihydroxyflavone (CAS 6674-39-1), a certified reference material (molecular formula C11H6Cl6O4, MW 414.88 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6Cl6O4 |
| Molecular Weight | 414.88 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Dihydroxyflavone Standards
- 6,3'-dihydroxyflavone (CAS 71592-46-6)
- Dihydroxyflavone, 6,7-(Rg) (CAS 38183-04-9)
- 7,8-Dihydroxyflavone (CAS 38183-03-8)
- 6,2'-Dihydroxyflavone (CAS 92439-20-8)
- 3,4'-Dihydroxyflavone (CAS 14919-49-4)
- 4',5-Dihydroxyflavone (CAS 6665-67-4)
- 3',4'-Dihydroxyflavone-4'-β-D-galactopyranoside sodium salt, 99% (CAS 517892-05-6)
- 3',4'-Dihydroxyflavone-4'-β-d-glucopyranoside sodium salt, 98% (CAS 517892-03-4)
Recommended Standards
- Loratadine Impurity 52 (CAS 1432057-93-6)
- N-(3-Chloro-4-fluorophenyl)-2-({4-[(E)-[(2-hydroxyphenyl)methylidene]amino]phenyl}sulfanyl)acetamide (CAS 882080-08-2)
- 8-Benzyl-4-(4-chlorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-08-4)
- N-Boc-N’-(2-chloro-Cbz)-L-lysine (CAS 54613-99-9)
- (4-Benzyl-1,4-diazepan-1-yl)(5-bromofuran-2-yl)methanone (CAS 1050587-25-1)
- 3-Aminoimidazo[1,2-a]pyridine-2-carbonitrile (CAS 82193-32-6)
- 2-(2,6-Dimethylmorpholino)pyrimidin-5-amine (CAS 1247459-59-1)
- (1-Phenyl-1H-1,2,3-triazol-4-yl)methyl 2,4-dichlorobenzoate (CAS 141581-65-9)
- 3-(4-hydroxybutyl)-1,3-thiazolidine-2,4-dione (CAS 1153126-36-3)
- 6-Bromo-3-cyclopropoxy-2-(methylthio)pyridine (CAS 1243385-61-6)
- n-Cyclohexyl-4-(4-nitrophenyl)-4,5-dihydrothiazol-2-amine (CAS 748778-14-5)
- 2-{[2-(1,3-benzoxazol-2-yl)propan-2-yl]amino}phenol (CAS 127894-03-5)
- Salbutamol Impurity 170 (CAS CATO-C4X-1176170)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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