2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid CAS 667435-73-6

Purity 97%+In StockPharmaceutical Standards
CAS No.667435-73-6
Molecular FormulaC18H14ClNO2
Molecular Weight311.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid CAS 667435-73-6 chemical structure

Description

As a certified reference material (CRM), 2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid (CAS 667435-73-6) is a high-purity analytical reference standard with the molecular formula C18H14ClNO2 and a molecular weight of 311.76 g/mol.

The molecular framework of 2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid (C18H14ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC18H14ClNO2
Molecular Weight311.76 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentCl-containing
Nitrogen Atoms1

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