2-((2-Chloro-6-fluorobenzyl)oxy)-3-methoxybenzaldehyde CAS 667437-86-7
| CAS No. | 667437-86-7 |
| Molecular Formula | C15H12ClFO3 |
| Molecular Weight | 294.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-((2-Chloro-6-fluorobenzyl)oxy)-3-methoxybenzaldehyde (CAS 667437-86-7), a certified reference material (molecular formula C15H12ClFO3, MW 294.71 g/mol) for analytical method development and quality control.
The molecular framework of 2-((2-Chloro-6-fluorobenzyl)oxy)-3-methoxybenzaldehyde (C15H12ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12ClFO3 |
| Molecular Weight | 294.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-n-(2-methoxyethyl)-2-nitrobenzenesulfonamide (CAS 1089581-75-8)
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- Methyl 4-[(2-chloro-6-fluorophenyl)methoxy]benzoate (CAS 128982-50-3)
- 2-((2-Chloro-6-fluorobenzyl)oxy)-5-methoxybenzaldehyde (CAS 1308240-99-4)
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- 3-Chloro-4-((2-fluorobenzyl)oxy)benzohydrazide (CAS 1706429-06-2)
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Recommended Standards
- 2-((2-Chloro-4-fluorobenzyl)oxy)-3-methoxybenzaldehyde (CAS 588692-21-1)
- 2-((2-Chlorothiazol-5-yl)methoxy)isoindoline-1,3-dione (CAS 339018-42-7)
- (3-Chloro-2-Fluorophenyl)(2,4-dimethoxyphenyl)methanone (CAS 680610-70-2)
- 2-(4-Chloro-3-fluorophenoxy)benzyl acetate (CAS 478032-51-8)
- 2-[(2H-1,3-Benzodioxol-5-yl)methylidene]-4,4-dimethyl-3-oxopentanenitrile (CAS 391649-79-9)
- (3',4'-Dimethyl-[1,1'-biphenyl]-2-yl)methanamine (CAS 946714-10-9)
- tert-Butyl (chloromethyl) succinate (CAS 432037-43-9)
- 5-(Allylthio)-1H-1,2,4-triazol-3-amine (CAS 399557-06-3)
- 2-Methyl-5-sulfanylbenzoic acid (CAS 84889-58-7)
- Stannane, (3-methoxy-2,5-thiophenediyl)bis[trimethyl- (CAS 128141-05-9)
- 4,4'-Oxybis(N,N-bis(oxiran-2-ylmethyl)aniline) (CAS 105359-67-9)
- 6-Chloro-1H-pyrrolo[3,2-c]pyridine-3-carbonitrile (CAS 1260381-90-5)
- Sucrose acetoisobutyrate (CAS 27216-37-1)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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