4-Chloro-2-(3-methoxyphenyl)-6-methylpyrimidine CAS 66744-02-3
| CAS No. | 66744-02-3 |
| Molecular Formula | C12H11ClN2O |
| Molecular Weight | 234.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-(3-methoxyphenyl)-6-methylpyrimidine (CAS 66744-02-3), molecular formula C12H11ClN2O and molecular weight 234.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-2-(3-methoxyphenyl)-6-methylpyrimidine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 234.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O |
| Molecular Weight | 234.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-chloro-N-quinolin-5-ylpropanamide (CAS 1000930-68-6)
- 6-chloro-n-[2-(pyridin-4-yl)ethyl]pyrimidin-4-amine (CAS 1016914-76-3)
- 5-Chloro-3-ethyl-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 1046784-61-5)
- 4-Chloro-6-(2-ethoxyphenyl)pyrimidine (CAS 1073485-22-9)
- 1098347-54-6 2-Chloro-N-quinolin-3-ylpropanamide MFCD11644441 (CAS 1098347-54-6)
- 3-Chloro-6-(4-ethoxyphenyl)pyridazine (CAS 1105194-82-8)
- 2-Chloro-3-(2-methoxybenzyl)pyrazine (CAS 1119450-87-1)
- 1-(5-Chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)ethanone (CAS 1140-37-0)
Recommended Standards
- 4-(Chloromethyl)-7,8-dihydrocyclopenta[g]-1-benzopyran-2(6H)-one (CAS 554423-45-9)
- 4-Chloro-3-((pyridin-2-yloxy)methyl)aniline (CAS 642084-80-8)
- 4-(Benzyloxy)-3-chlorophenol (CAS 86902-27-4)
- 4-Chloro-3-(pyridin-3-yloxymethyl)phenylamine (CAS 642084-31-9)
- Piperophos (CAS 24151-93-7)
- 2-Acetylphenothiazine (CAS 6631-94-3)
- Trimethyl(3-methylbut-2-en-1-yl)silane (CAS 18293-99-7)
- Dihydroquinine hydrobromide (CAS 85153-19-1)
- 4-Bromo-1-methyl-1H-indazole-3-carboxylic acid (CAS 1363380-97-5)
- 10,13-Difluoro-2,8-dioxa-5-azatricyclo[7.4.0.0,3,7]trideca-1(9),10,12-triene hydrochloride (CAS 1909318-59-7)
- n-(5-Bromo-4-formyl-1,3-thiazol-2-yl)-n-[3-(trifluoromethyl)phenyl]acetamide (CAS 790272-40-1)
- 2-Amino-3-fluoropropan-1-ol hydrochloride (CAS 1384428-30-1)
- 1-Methoxyisoquinoline (CAS 23724-93-8)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com