5-Bromo-2,3,4,6-tetramethyl-2,3-dihydrobenzofuran CAS 667466-08-2

Purity 97%+In StockPharmaceutical Standards
CAS No.667466-08-2
Molecular FormulaC12H15BrO
Molecular Weight255.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-2,3,4,6-tetramethyl-2,3-dihydrobenzofuran CAS 667466-08-2 chemical structure

Description

The occurrence of 5-Bromo-2,3,4,6-tetramethyl-2,3-dihydrobenzofuran is closely related to a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Bromo-2,3,4,6-tetramethyl-2,3-dihydrobenzofuran (CAS 667466-08-2), molecular formula C12H15BrO and molecular weight 255.15 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Bromo-2,3,4,6-tetramethyl-2,3-dihydrobenzofuran (C12H15BrO) is characterized by a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-2,3,4,6-tetramethyl-2,3-dihydrobenzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H15BrO
Molecular Weight255.15 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentBr-containing

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