Metaxalone Impurity 1 CAS 66766-07-2
| CAS No. | 66766-07-2 |
| Molecular Formula | C11H17NO2 |
| Molecular Weight | 195.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metaxalone Impurity 1.
CATO supplies Metaxalone Impurity 1 (CAS 66766-07-2), a pharmacopoeial impurity reference standard (molecular formula C11H17NO2, MW 195.26 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Metaxalone Impurity 1 (C11H17NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Metaxalone Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H17NO2 |
| Molecular Weight | 195.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 1 |
Related Metaxalone Standards
Recommended Standards
- Mirogabalin Impurity 151 (CAS CATO-C4X-2924151)
- Benzyl 2-Methylbutyrate-d3 (CAS 1215566-12-3)
- Mirogabalin Impurity 150 (CAS CATO-C4X-2924150)
- Aldicarb-(<I>N</I>-<I>methyl</I>-<SUP>13</SUP>C,d<SUB>3</SUB> <I>Carbamoyl< /I>-<SUP>13</SUP>C) (CAS 1261170-75-5)
- Etoposide EP Impurity Q (CAS 153975-26-9)
- Mirabegron Impurity 126 (CAS CATO-C4X-1032126)
- Tenofovir alafenamide impurity 86 (CAS CATO-C4X-179786)
- 6-Aminopyridine-2,4-diol (CAS 104767-38-6)
- Olsalazine Sodium (CAS 6054-98-4)
- (1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)methanol (CAS 761440-57-7)
- 2,5-Dimethyl-n-(prop-2-en-1-yl)benzene-1-sulfonamide (CAS 749920-68-1)
- 2-phenylquinolin-4-ol (CAS 1144-20-3)
- 2-(3-Hydroxyphenyl)acetamide (CAS 22446-41-9)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com