2-Chloro-6-fluorobenzonitrile CAS 668-45-1
| CAS No. | 668-45-1 |
| Molecular Formula | C7H3ClFN |
| Molecular Weight | 155.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-fluorobenzonitrile.
2-Chloro-6-fluorobenzonitrile (CAS 668-45-1), molecular formula C7H3ClFN and molecular weight 155.56 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H3ClFN, 2-Chloro-6-fluorobenzonitrile contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 155.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-6-fluorobenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClFN |
| Molecular Weight | 155.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-fluorophenylisocyanide (CAS 1030269-27-2)
- 4-Chloro-3-fluorobenzonitrile (CAS 110888-15-8)
- 3-Chloro-4-fluorobenzonitrile (CAS 117482-84-5)
- 2-Chloro-4-ethynyl-5-fluoropyridine (CAS 1211539-66-0)
- 2-Chloro-4-ethynyl-3-fluoropyridine (CAS 1211589-16-0)
- 2-Chloro-5-ethynyl-3-fluoropyridine (CAS 1256785-45-1)
- 2-Chloro-3-ethynyl-5-fluoropyridine (CAS 1256789-32-8)
- 5-Chloro-2-ethynyl-3-fluoropyridine (CAS 1256808-79-3)
Recommended Standards
- 2-Chloro-5-fluorobenzonitrile (CAS 57381-56-3)
- 3-Chloro-2-fluorobenzonitrile (CAS 94087-40-8)
- 2-Chloro-3-fluorobenzonitrile (CAS 874781-08-5)
- 3-Chloro-4-fluorophenylisocyanide (CAS 602261-99-4)
- 6-Chloro-N-(3-chlorophenyl)-2H-chromene-3-carboxamide (CAS 338759-58-3)
- Methyl 1-acetyl-3-oxopiperidine-4-carboxylate (CAS 1174007-42-1)
- 4-hydrazinyl-1-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 1565576-49-9)
- (S)-2-(2-(Trifluoromethyl)phenyl)piperidine hydrochloride (CAS 1391478-72-0)
- 2-(4-Nitrophenoxy)butanoic acid (CAS 120552-01-4)
- 2-((1-Cyanoethyl)amino)benzoic acid (CAS 28354-43-0)
- 1,1,1-Trifluoro-3-(1-methyl-1h-imidazol-2-yl)propan-2-ol (CAS 100282-72-2)
- N-cetylmorpholine (CAS 25727-91-7)
- 4-(4-Amino-6-chloro-1,3,5-triazin-2-yl)piperazin-2-one (CAS 1220029-47-9)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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