2',4',6'-Trimethyl-[1,1'-biphenyl]-4-amine CAS 66818-61-9

Purity 97%+In StockPharmaceutical Standards
CAS No.66818-61-9
Molecular FormulaC15H17N
Molecular Weight211.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2',4',6'-Trimethyl-[1,1'-biphenyl]-4-amine CAS 66818-61-9 chemical structure

Description

2',4',6'-Trimethyl-[1,1'-biphenyl]-4-amine (CAS 66818-61-9) is a high-purity analytical reference standard with the molecular formula C15H17N and a molecular weight of 211.30 g/mol.

The molecular framework of 2',4',6'-Trimethyl-[1,1'-biphenyl]-4-amine (C15H17N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H17N
Molecular Weight211.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Nitrogen Atoms1

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