Ethyl (2-chlorobenzoyl)glycinate CAS 66824-94-0
| CAS No. | 66824-94-0 |
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl (2-chlorobenzoyl)glycinate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl (2-chlorobenzoyl)glycinate (CAS 66824-94-0) is a high-purity analytical reference standard with the molecular formula C11H12ClNO3 and a molecular weight of 241.67 g/mol.
Ethyl (2-chlorobenzoyl)glycinate (C11H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-[(4-Chlorobenzoyl)amino]-2-methylpropanoic acid (CAS 129973-02-0)
- Ethyl (3-chlorobenzoyl)glycinate (CAS 66824-95-1)
- Ethyl (4-chlorobenzoyl)glycinate (CAS 39735-52-9)
- 2-(4-Chlorobenzoyl)-4-methylmorpholine (CAS 1427379-80-3)
- 2-(4-Chlorobenzoyl)-N-methylhydrazine-1-carbothioamide (CAS 29527-10-4)
- 1-(2-Chlorobenzoyl)-2-methylpiperazine (CAS 1240565-27-8)
- 1-(4-Chlorobenzoyl)-2-methylpiperazine (CAS 1240565-53-0)
- 1-(2-Chlorobenzoyl)-3-methylpiperazine (CAS 1240567-14-9)
Recommended Standards
- Benzyl (3-chloro-3-oxopropyl)carbamate (CAS 51513-97-4)
- Acridine-9-carbonyl chloride (CAS 66074-67-7)
- 7-Chloro-N-propylbenzo[d][1,3]dioxole-5-carboxamide (CAS 878126-55-7)
- Ethyl [(3-chloro-2-methylphenyl)carbamoyl]formate (CAS 341940-71-4)
- Ethyl 2-(4-(hydroxymethyl)phenyl)propanoate (CAS 118618-33-0)
- 4-(1H-Pyrrol-1-yl)picolinimidamide hydrochloride (CAS 1179361-58-0)
- 2-(2-(PYRROLIDIN-1-YLMETHYL)PHENYL)ACETIC ACID (CAS 933717-24-9)
- N-{[2-chloro-6-(1H-pyrrol-1-yl)phenyl]methyl}-3-fluoro-4-(trifluoromethyl)benzamide (CAS 866043-39-2)
- 2-Propenoic acid, sodium salt (1:1), homopolymer (CAS 25549-84-2)
- cis-3-hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1690177-86-6)
- (3aR,8aR)-N,N-diisopropyl-2,2-dimethyl-4,4,8,8-tetraphenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-amine (CAS 213843-93-7)
- 1-Cyclopentylpentan-1-one (CAS 6636-80-2)
- 3-(3-Bromo-5-fluorophenyl)acrylic acid (CAS 887268-21-5)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com