1,2-Dibromo-4-tert-butylbenzene CAS 6683-75-6
| CAS No. | 6683-75-6 |
| Molecular Formula | C10H12Br2 |
| Molecular Weight | 292.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,2-Dibromo-4-tert-butylbenzene is closely related to bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1,2-Dibromo-4-tert-butylbenzene (CAS 6683-75-6), molecular formula C10H12Br2 and molecular weight 292.01 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,2-Dibromo-4-tert-butylbenzene (C10H12Br2) is characterized by bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12Br2 |
| Molecular Weight | 292.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br-containing |
Related Dibromo Standards
- 3,4-Dibromo-n-butylbenzene (CAS 1160574-94-6)
- 1,3-Dibromo-5-(tert-butyl)benzene (CAS 129316-09-2)
- 1,4-Dibromo-2,3,5,6-tetramethylbenzene (CAS 1646-54-4)
- 1,2-Dibromo-3,4,5,6-tetramethylbenzene (CAS 36321-73-0)
- 1,3-Dibromo-5-isopropyl-2-methylbenzene (CAS 2624417-82-7)
- 1,4-Dibromo-2,5-diethylbenzene (CAS 40787-48-2)
- 2,5-Dibromo-1,3-diethylbenzene (CAS 314084-64-5)
- 3,5-Dibromo-4-n-butylbenzene (CAS 75894-94-9)
Recommended Standards
- 1,2-Bis(bromomethyl)-4,5-dimethylbenzene (CAS 60070-06-6)
- 1,4-Bis(2-bromoethyl)benzene (CAS 4542-72-7)
- 1,4-Bis(bromomethyl)-2,5-dimethylbenzene (CAS 35168-62-8)
- 1-Bromo-4-(3-bromo-2-methylpropyl)benzene (CAS 1483134-51-5)
- 4-(Benzyl(ethyl)amino)-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 860785-50-8)
- 5-Bromo-2,3-dihydrobenzofuran (CAS 66826-78-6)
- Z-Ala-Arg-OH (CAS 50465-91-3)
- (2-Ethoxypyridin-3-yl)methanamine dihydrochloride (CAS 1268982-87-1)
- (±)-Citronellal (CAS 106-23-0)
- 7-Amino-4-methyl-1H-indazole (CAS 952183-44-7)
- Methyl 2-bromo-7-chlorothiazolo[5,4-b]pyridine-6-carboxylate (CAS 2592316-87-3)
- Isopropyl (3-methylbenzofuran-2-yl)carbamate (CAS 61307-29-7)
- 1,8-Diazaspiro[4.5]decane-8-carboxylic acid,1,1-dimethylethyl ester (CAS 937729-06-1)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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