2-((3,4-Dihydroquinolin-1(2H)-yl)methylene)malononitrile CAS 6687-85-0
| CAS No. | 6687-85-0 |
| Molecular Formula | C18H10Cl4N2O2 |
| Molecular Weight | 428.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((3,4-Dihydroquinolin-1(2H)-yl)methylene)malononitrile (CAS 6687-85-0) is a high-purity analytical reference standard with the molecular formula C18H10Cl4N2O2 and a molecular weight of 428.10 g/mol.
Structurally, 2-((3,4-Dihydroquinolin-1(2H)-yl)methylene)malononitrile (C18H10Cl4N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 428.10 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-((3,4-Dihydroquinolin-1(2H)-yl)methylene)malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl4N2O2 |
| Molecular Weight | 428.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dihydroquinolin Standards
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 332376-19-9)
- 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-ethoxyphenyl)acetamide (CAS 898456-24-1)
- 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-3-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 1040632-71-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 483284-59-9)
- 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide (CAS 898455-72-6)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-(2-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 851274-39-0)
- N-(4-(2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thiazol-2-yl)thiophene-2-carboxamide (CAS 921874-99-9)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone (CAS 332357-73-0)
Recommended Standards
- Methyl Pentadecafluorooctanoate (CAS 376-27-2)
- 4-Bromo-5-((2,4-dichlorophenoxy)methyl)-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1024052-48-9)
- 1H,1H,2H,2H-Perfluorooctanephosphonic acid (CAS 252237-40-4)
- Benzbromarone-d4 (CAS CATO-C4X-22502)
- (S)-6'-Chloro-3',4,4',5-tetrahydro-2H,2'H-spiro[benzo[b][1,4]oxazepine-3,1'-naphthalene]-7-carboxylic acid (CAS 1883726-83-7)
- 2-(3-(4-Methoxyphenyl)acrylamido)benzoic acid (CAS 22780-32-1)
- 7-Fluoro-6-methoxyquinolin-4(1H)-one (CAS 948573-52-2)
- Methyl 4-chloro-6-cyclopropylpyrimidine-2-carboxylate (CAS 1529210-56-7)
- 4-Butyl-4'-iodobiphenyl (CAS 199982-02-0)
- 2-((2,5-Dimethylphenyl)thio)ethanol (CAS 16600-60-5)
- 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 1426320-86-6)
- 2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]acetonitrile (CAS 329978-21-4)
- N-(2,4-dimethylphenyl)-4-hydroxypiperidine-1-carbothioamide (CAS 402479-57-6)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com