2-(4-(4-Methylpiperazin-1-yl)benzylidene)malononitrile CAS 66883-96-3
| CAS No. | 66883-96-3 |
| Molecular Formula | C15H16N4 |
| Molecular Weight | 252.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-(4-(4-Methylpiperazin-1-yl)benzylidene)malononitrile (CAS 66883-96-3), a certified reference material (molecular formula C15H16N4, MW 252.31 g/mol) for analytical method development and quality control.
2-(4-(4-Methylpiperazin-1-yl)benzylidene)malononitrile (C15H16N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H16N4 |
| Molecular Weight | 252.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 4 |
Related Methylpiperazin Standards
- 1-(2-(4-Methylpiperazin-1-yl)-2-oxoethyl)-1H-pyrazole-4-carboxylic acid (CAS 1006493-10-2)
- 5-Acetyl-1-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 320420-08-4)
- 4-((4-Methylpiperazin-1-yl)methyl)benzoyl chloride (CAS 148077-69-4)
- (5-(4-Methylpiperazin-1-yl)-2-nitrophenyl)methanol (CAS 1002556-21-9)
- (2-(4-Methylpiperazin-1-yl)-5-nitrophenyl)methanol (CAS 802541-80-6)
- [3-(4-Methylpiperazin-1-yl)propyl]-(2-thienylmethyl)amine (CAS 1042608-39-8)
- 7-(4-Methylpiperazin-1-yl)thiazolo[4,5-d]pyrimidin-5-amine (CAS 1363405-25-7)
- Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate, 97% (CAS 1116339-74-2)
Recommended Standards
- 2-(4-(1-Aminoethyl)phenyl)isoindolin-1-one (CAS 344339-81-7)
- 2-(4-(8-Methylimidazo[1,2-a]pyridin-2-yl)phenyl)ethanol (CAS 62705-93-5)
- 2-(4-((Isopropylamino)methyl)-2-methoxyphenoxy)acetamide (CAS 940202-62-0)
- 2-(4-(Dimethylamino)phenyl)-1H-benzo[d]imidazol-5-amine (CAS 40655-14-9)
- 1,2,3,4-tetrahydropyrido[3,4-b]pyrazine (CAS 35808-41-4)
- Ethyl 4-bromo-5-chloro-8-methoxyquinoline-3-carboxylate (CAS 1242260-39-4)
- N-(5-Aminopentyl)acetamide (CAS 32343-73-0)
- Lodoxamide Impurity 3 (CAS 617-36-7)
- 2,2'-(2-Chloro-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 2762233-91-8)
- tert-Butyl 6-bromo-2-fluoro-3-methylbenzoate (CAS 2379321-33-0)
- 6-(Bromomethyl)isoquinoline hydrobromide (CAS 188861-57-6)
- (4-(Methylamino)piperidin-1-yl)(3-methylthiophen-2-yl)methanone hydrochloride (CAS 1353962-63-6)
- 1-(2-Phenylethyl)piperazine (CAS 5321-49-3)
- Hexapeptide-10 (CAS 146439-94-3)
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