Pregnenolone Impurity 9 CAS 66905-18-8
| CAS No. | 66905-18-8 |
| Molecular Formula | C22H30O4 |
| Molecular Weight | 358.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pregnenolone Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Pregnenolone Impurity 9 (CAS 66905-18-8), a pharmacopoeial impurity reference standard (molecular formula C22H30O4, MW 358.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Pregnenolone Impurity 9 (C22H30O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C22H30O4 |
| Molecular Weight | 358.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
Related Pregnenolone Standards
- Pregnenolone Acetate (CAS 1778-02-5)
- Pregnenolone Impurity 14 (CAS 911452-26-1)
- Pregnenolone Impurity 13 (CAS 68520-34-3)
- Pregnenolone Impurity 12 (CAS 66880-01-1)
- Pregnenolone 17α-Acetoxy (CAS 2381-45-5)
- Pregnenolone Carbonitrile (CAS 1434-54-4)
- Pregnenolone Impurity 10 (CAS 1173-11-1)
- Pregnenolone Isobutyrate (CAS CATO-C4X-21916)
Recommended Standards
- Methylprednisolone Impurity 81 (CAS 82332-00-1)
- tert-butyl (R)-(2,5-dimethyl-4-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-2,3-dihydrobenzofuran-7-yl)carbamate (CAS CATO-C4X-30133)
- Methylprednisolone Impurity 57 (CAS 1048031-80-6)
- Iloprost Impurity 3 (CAS CATO-C4X-32023)
- Posaconazole Impurity 62 (CAS CATO-C4X-120862)
- Flomoxef Impurity 19 (CAS CATO-C4X-138219)
- Orforglipron impurity 128 (CAS CATO-C4X-3234128)
- 2-(piperidin-4-yl)-4-(pyrimidin-5-yl)pyrimidine (CAS 2059936-51-3)
- 1-(2-Chloro-6-methylpyridin-4-yl)ethanone (CAS 890406-52-7)
- 5-Nitro-6-(piperidin-1-yl)quinoline (CAS 19979-55-6)
- 3-(6-Methylbenzo[d]oxazol-2-yl)aniline (CAS 292644-37-2)
- Nemonoxacin (CAS 378746-64-6)
- 1-(6-Aminohexyl)-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 790167-37-2)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
Why CATO?
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