Methyl 6-cyano-7-methyl-1,5-dioxo-1,2,3,5-tetrahydroindolizine-2-carboxylate CAS 66917-18-8
| CAS No. | 66917-18-8 |
| Molecular Formula | C12H10N2O4 |
| Molecular Weight | 246.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 6-cyano-7-methyl-1,5-dioxo-1,2,3,5-tetrahydroindolizine-2-carboxylate (CAS 66917-18-8) is a high-purity analytical reference standard with the molecular formula C12H10N2O4 and a molecular weight of 246.22 g/mol.
Structurally, Methyl 6-cyano-7-methyl-1,5-dioxo-1,2,3,5-tetrahydroindolizine-2-carboxylate (C12H10N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 246.22 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Methyl 6-cyano-7-methyl-1,5-dioxo-1,2,3,5-tetrahydroindolizine-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10N2O4 |
| Molecular Weight | 246.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- Ethyl 3-(4-cyano-2-nitrophenyl)acrylate (CAS 104291-52-3)
- Ethyl 2-Cyano-3-(3-nitrophenyl)acrylate (CAS 14394-75-3)
- Ethyl 2-Cyano-3-(3-nitrophenyl)acrylate (CAS 18925-00-3)
- 6-Cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylic Acid Methyl Ester (CAS 73427-92-6)
- Ethyl 2-cyano-3-(2-nitrophenyl)acrylate (CAS 5470-58-6)
- Ethyl 2-Cyano-3-(4-nitrophenyl)acrylate (CAS 2286-33-1)
- 2-(4-Cyano-2-methoxyphenoxy)-N-cyclopropylacetamide (CAS 850301-77-8)
- Ethyl 3-cyano-1,2-dihydro-6-(1-methylcyclopropyl)-2-oxo-4-pyridinecarboxylate (CAS 2420426-80-6)
Recommended Standards
- Methyl 5,6-Dihydroxy-2-phenylpyrimidine-4-carboxylate (CAS 62222-36-0)
- N-(1-(2-Nitrophenyl)-1H-pyrazol-4-yl)acetamide (CAS 62537-89-7)
- Methyl 4-amino-5-benzoylisoxazole-3-carboxylate (CAS 647862-64-4)
- N-(1-(3-Nitrophenyl)-1H-pyrazol-4-yl)acetamide (CAS 62537-90-0)
- 4-Ethynyl-2-nitroaniline (CAS 656798-50-4)
- 6-Cyano-2-naphthol (CAS 52927-22-7)
- 2-(4-(2-Methoxyphenyl)piperazin-1-yl)-5-(prop-2-yn-1-ylthio)-1,3,4-thiadiazole (CAS 1105252-40-1)
- Ethyl 5-fluoro-3-hydroxybenzo[b]thiophene-2-carboxylate (CAS 2089944-02-3)
- 16-bromohexadecan-1-ol (CAS 59101-28-9)
- 1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]ethan-1-one (CAS 1060815-96-4)
- 3-(But-2-enoyl)thiazolidine-4-carboxylic acid (CAS 1101902-78-6)
- 1-(4-Methoxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid (CAS 3807-58-7)
- (Z)-Octadec-13-enoic acid (CAS 13126-39-1)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com