3-Butoxy-4-methoxybenzoic acid CAS 66924-20-7
| CAS No. | 66924-20-7 |
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Butoxy-4-methoxybenzoic acid (CAS 66924-20-7) is a high-purity analytical reference standard with the molecular formula C12H16O4 and a molecular weight of 224.25 g/mol.
3-Butoxy-4-methoxybenzoic acid (C12H16O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
Related Butoxy Standards
- 2-Butoxy-4-methoxybenzoic acid (CAS 95420-80-7)
- 4-Butoxy-3-hydroxyphenylacetic Acid (CAS 2006277-38-7)
- 4-Butoxy-3-methoxybenzoic acid (CAS 3535-34-0)
- methyl 4-butoxy-2-hydroxybenzoate (CAS 86840-96-2)
- 1-(tert-Butoxy)-4-cyclopropoxy-2-fluorobenzene (CAS 1243284-79-8)
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Recommended Standards
- 3'-Acetyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 400750-70-1)
- 3-ethoxy-4-isopropoxybenzoic acid (CAS 52009-54-8)
- 3'-Acetyl-[1,1'-biphenyl]-2-carbaldehyde (CAS 400745-14-4)
- 3-Ethoxy-4-propoxybenzoic acid (CAS 52009-55-9)
- 3-(1h-1,2,3-Benzotriazol-1-yl)propanenitrile (CAS 6946-09-4)
- D-erythro-Sphingosine-N-tert-butyloxycarbonyl-O-tert-butyldimethylsilyl (CAS 342655-72-5)
- 1-(tert-Butyl) 3-methyl 5-((tert-butyldimethylsilyl)oxy)piperidine-1,3-dicarboxylate (CAS 1415793-76-8)
- 1-Benzyl-2-(methylsulfonyl)piperazine dihydrochloride (CAS 1333901-62-4)
- 3,3'-Bis(3,5-dichlorophenyl)-[1,1'-binaphthalene]-2,2'-diol (CAS 1706459-29-1)
- 5-(Cyclopentyloxy)-2-fluorophenol (CAS 1881328-11-5)
- Saxagliptin Impurity 19 (CAS 681282-72-4)
- 2-(3-(4-Nitrobenzyl)-2,4,5-trioxoimidazolidin-1-yl)acetic acid (CAS 175293-31-9)
- tert-Butyl (S)-3-(2-fluorobenzyl)piperazine-1-carboxylate (CAS 1240590-08-2)
- Uremic Pentapeptide (CAS 71494-20-7)
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