Flubendazole Impurity E CAS 66939-00-2
| CAS No. | 66939-00-2 |
| Molecular Formula | C16H12FN3O3 |
| Molecular Weight | 313.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Flubendazole Impurity E (C16H12FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Flubendazole Impurity E (CAS 66939-00-2) is a high-purity analytical reference standard with the molecular formula C16H12FN3O3 and a molecular weight of 313.28 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12FN3O3 |
| Molecular Weight | 313.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Flubendazole Standards
- Flubendazole (CAS 31430-15-6)
- Flubendazole D3 (methyl D3) (CAS 1173021-08-3)
- Flubendazole EP Impurity F (CAS 132119-20-1)
- Flubendazole EP Impurity A (CAS CATO-C4X-24384)
- Flubendazole EP Impurity G (CAS CATO-C4X-24387)
- Flubendazole EP Impurity C (CAS 1097107-40-8)
- Flubendazole EP Impurity D (CAS 1515807-30-3)
Recommended Standards
- Ethyl 3,5-dimethyl-1-(3-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carboxylate (CAS 477711-15-2)
- N-ethyl-4-(4-methoxyphenoxy)-6-(trifluoromethyl)pyrimidin-2-amine (CAS 339010-95-6)
- 4-Fluoro-3-[(6-methyl-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-benzoic acid (CAS 2088945-60-0)
- 4-fluoro-N-(7-oxo-6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-yl)benzenecarboxamide 861209-45-2 KS-00001UZE (CAS 861209-45-2)
- 2-Cyclohexylisonicotinohydrazide (CAS 1706455-10-8)
- 3-(Chloromethyl)-1,4,6,7-tetrahydropyrano[4,3-c]pyrazole hydrochloride (CAS 2138021-00-6)
- N-(3,4-dichlorophenyl)acrylamide (CAS 15271-54-2)
- 5-Bromobenzofurazan 1-oxide (CAS 36387-84-5)
- N'-((1H-Indol-3-yl)methylene)-4-((4-chlorobenzyl)oxy)benzohydrazide (CAS 339201-57-9)
- (Z)-2-(4-(4-(tert-butyl)phenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-N'-hydroxyacetimidamide (CAS 866020-28-2)
- 4-(Aminomethyl)octane (CAS 857818-18-9)
- n-Methyl-1-(5-phenylisoxazol-3-yl)methanamine (CAS 852431-02-8)
- tert-Butyl (2-hydroxyphenethyl)carbamate (CAS 20286-84-4)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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