2-Amino-N-(3-nitrophenyl)thiophene-3-carboxamide CAS 669740-08-3
| CAS No. | 669740-08-3 |
| Molecular Formula | C11H9N3O3S |
| Molecular Weight | 263.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-N-(3-nitrophenyl)thiophene-3-carboxamide.
2-Amino-N-(3-nitrophenyl)thiophene-3-carboxamide (CAS 669740-08-3), molecular formula C11H9N3O3S and molecular weight 263.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Amino-N-(3-nitrophenyl)thiophene-3-carboxamide (C11H9N3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9N3O3S |
| Molecular Weight | 263.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
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Recommended Standards
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- 3-(4-Fluorophenyl)-1-phenyl-1H-pyrazole-4-carbonitrile (CAS 392251-92-2)
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- Ethyl 6-chloro-3-methoxy-1,2,4-triazine-5-carboxylate (CAS 1260672-36-3)
- N-(sec-Butyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide (CAS 697791-13-2)
- 3,6-Dimethyl-1-phenyl-5-(pyrrolidin-1-yl)pyrimidine-2,4(1H,3H)-dione (CAS 32150-61-1)
- 4-Cyclopropoxy-2-fluoro-1-isopropylbenzene (CAS 1243472-03-8)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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