Methyl 5-carbamoyl-2-(2-chloroacetamido)-4-methylthiophene-3-carboxylate CAS 669747-30-2
| CAS No. | 669747-30-2 |
| Molecular Formula | C10H11ClN2O4S |
| Molecular Weight | 290.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 290.72 g/mol gives Methyl 5-carbamoyl-2-(2-chloroacetamido)-4-methylthiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 5-carbamoyl-2-(2-chloroacetamido)-4-methylthiophene-3-carboxylate (CAS 669747-30-2), molecular formula C10H11ClN2O4S and molecular weight 290.72 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 5-carbamoyl-2-(2-chloroacetamido)-4-methylthiophene-3-carboxylate (C10H11ClN2O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-carbamoyl-2-(2-chloroacetamido)-4-methylthiophene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN2O4S |
| Molecular Weight | 290.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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