1-(6-Chloro-2-hydroxy-4-phenylquinolin-3-yl)piperidine-3-carboxylic acid CAS 669754-82-9
| CAS No. | 669754-82-9 |
| Molecular Formula | C21H19ClN2O3 |
| Molecular Weight | 382.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 382.84 g/mol gives 1-(6-Chloro-2-hydroxy-4-phenylquinolin-3-yl)piperidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(6-Chloro-2-hydroxy-4-phenylquinolin-3-yl)piperidine-3-carboxylic acid (CAS 669754-82-9) is a high-purity analytical reference standard with the molecular formula C21H19ClN2O3 and a molecular weight of 382.84 g/mol.
1-(6-Chloro-2-hydroxy-4-phenylquinolin-3-yl)piperidine-3-carboxylic acid (C21H19ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(6-Chloro-2-hydroxy-4-phenylquinolin-3-yl)piperidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN2O3 |
| Molecular Weight | 382.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (5Z)-5-({4-[(2-chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl}methylidene)-1,3-thiazolidine-2,4-dione (CAS 866131-59-1)
- 2-[2-(5-Chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-vinyl]-6-methoxy-benzoic acid methyl ester (CAS 365542-59-2)
- 5-Chloro-1-methyl-3-phenyl-4-(((3-(trifluoromethyl)phenyl)thio)methyl)-1H-pyrazole (CAS 318234-16-1)
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Recommended Standards
- 1-(4-Chlorophenyl)-3-[(1S,2S)-2-(hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]urea (CAS 477713-62-5)
- 1,3-Diethyl 2-(3-chlorophenyl)-4-hydroxy-4-methyl-6-oxocyclohexane-1,3-dicarboxylate (CAS 4759-55-1)
- 1-(4-Chlorobenzyl)-N-(4-ethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400077-76-1)
- 1-(2-Chlorobenzyl)-N-(4-ethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400077-77-2)
- 7-methyl-[1,2,4]triazolo[4,3-a]pyrimidine-3-carboxylic acid (CAS 1256643-42-1)
- Butanedioic acid, 2-methylene-, 1,4-di-2-propen-1-yl ester (CAS 2767-99-9)
- methyl 2-[3-(2-hydroxyethyl)-1-bicyclo[1.1.1]pentanyl]acetate (CAS 2168032-82-2)
- 1-(Phenyl(4-(trifluoromethyl)phenyl)methyl)piperazinehydrochloride (CAS 1189493-88-6)
- 4-Methyl-3-nitrophenyl isocyanate (CAS 13471-69-7)
- N-[1-(pyrrolidin-3-yl)-1H-pyrazol-3-yl]acetamide dihydrochloride (CAS 1803570-53-7)
- Dimethyl 5-Chloroisophthalate (CAS 20330-90-9)
- 3-Ethylamino-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 887587-15-7)
- tert-Butyl Alcohol-OD (CAS 3972-25-6)
- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
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