6-Amino-5-(2-chloroacetyl)-1-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione CAS 67130-67-0
| CAS No. | 67130-67-0 |
| Molecular Formula | C8H10ClN3O3 |
| Molecular Weight | 231.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 231.64 g/mol gives 6-Amino-5-(2-chloroacetyl)-1-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Amino-5-(2-chloroacetyl)-1-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 67130-67-0) is a high-purity analytical reference standard with the molecular formula C8H10ClN3O3 and a molecular weight of 231.64 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 6-Amino-5-(2-chloroacetyl)-1-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10ClN3O3 |
| Molecular Weight | 231.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- Ethyl 2-(5-amino-6-chloropyrimidin-4-yl)hydrazinecarboxylate (CAS 6969-82-0)
- 2-Amino-3-chloro-4,6-dimethoxybenzoic acid (CAS 1164251-94-8)
- 2-(2-Amino-6-(chloromethyl)-3-(difluoromethyl)pyridin-4-yl)acetonitrile (CAS 1804721-97-8)
- 2-(2-Amino-4-(chloromethyl)-5-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1805229-83-7)
- 2-(2-Amino-5-(chloromethyl)-4-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1805229-92-8)
- 2-(6-Amino-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-yl)acetonitrile (CAS 1805332-87-9)
- 2-(2-Amino-3-(chloromethyl)-6-(difluoromethyl)pyridin-4-yl)acetonitrile (CAS 1805339-23-4)
- 2-(6-Amino-4-(chloromethyl)-5-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1806798-01-5)
Recommended Standards
- 5-chloro-3-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 91322-01-9)
- 7-(4-Chlorophenyl)tetrazolo[1,5-a]pyrimidine (CAS 320416-70-4)
- 4-Chloro-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carbonitrile (CAS 338405-09-7)
- 7-Chloro-2-phenyl[1,3]oxazolo[5,4-d]pyrimidine (CAS 33360-19-9)
- 1-(4-Isopropylphenyl)cyclobutane-1-carboxylic acid (CAS 926187-55-5)
- (2-Phenylethynyl)(trimethylphosphine)gold (CAS 89989-62-8)
- (S)-tert-Butyl 2-oxa-8-azaspiro[4.5]decan-4-ylcarbamate (CAS 2098564-13-5)
- 6-chloro-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one (CAS 304861-88-9)
- N2-Cyclopropyl-N3-(piperidin-4-yl)quinoxaline-2,3-diamine hydrochloride (CAS 1185319-96-3)
- Tert-butyl 3-(((5-bromo-3-iodopyridin-2-yl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 1186311-10-3)
- 5-(Benzyloxy)-1H-imidazole-4-carboxamide (CAS 88100-22-5)
- 3-Bromo-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1774894-72-2)
- Lapatinib Impurity 27 (CAS 104458-24-4)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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