2-(Trifluoromethyl)pyrimidine-4,6-diamine CAS 672-46-8
| CAS No. | 672-46-8 |
| Molecular Formula | C5H5F3N4 |
| Molecular Weight | 178.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrile group, fluorine substitution, 2-(Trifluoromethyl)pyrimidine-4,6-diamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Trifluoromethyl)pyrimidine-4,6-diamine (CAS 672-46-8) is a high-purity analytical reference standard with the molecular formula C5H5F3N4 and a molecular weight of 178.12 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5F3N4 |
| Molecular Weight | 178.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)pyrimidine-4,5-diamine (CAS 1023817-05-1)
- (6-Trifluoromethyl-pyrazin-2-yl)-hydrazine (CAS 1197238-33-7)
- 5-(Trifluoromethyl)pyrimidine-2,4-diamine (CAS 1243389-47-0)
- 1-(Trifluoromethyl)-1H-pyrazole-4-carboximidamide (CAS 1551552-78-3)
- 4-Methyl-6-(trifluoromethyl)-1,3,5-triazin-2-amine (CAS 29181-69-9)
- 6-(Trifluoromethyl)pyrimidine-4,5-diamine (CAS 23663-20-9)
- 2-(3-(Trifluoromethyl)-1H-pyrazol-1-yl)acetaldehyde (CAS 1007551-55-4)
- 1-(2-(Trifluoromethyl)-1H-imidazol-5-yl)ethan-1-one (CAS 103747-79-1)
Recommended Standards
- 3-[Ethyl(hydroxy)phosphoryl]-2-butenoic Acid (CAS 33472-67-2)
- 4-Hydrazinyl-2-(trifluoromethyl)pyrimidine (CAS 236746-88-6)
- 5-Hydrazinyl-2-(trifluoromethyl)pyrimidine (CAS 123418-92-8)
- 3-Hydrazinyl-6-(trifluoromethyl)pyridazine (CAS 1161005-11-3)
- 4-Chloro-2-(((1-hydroxybutan-2-yl)amino)methyl)phenol (CAS 1042623-95-9)
- 4-[2-(quinolin-2-yl)ethenyl]benzoic acid (CAS 1000277-67-7)
- 4-Chloro-1-(2,5-difluorophenyl)butan-1-one (CAS 1216260-42-2)
- 2,3-Dibromo-4-(hydroxymethyl)-6-methoxyphenol (CAS 1940-81-4)
- O-(3-phenoxypropyl)hydroxylamine (CAS 82703-22-8)
- 5-methyl-1,3-benzothiazole (CAS 2942-16-7)
- 5-[(4-bromo-1h-pyrazol-1-yl)methyl]furan-2-carboxylic acid (CAS 312308-99-9)
- 1-[(5-Methylisoxazol-3-yl)carbonyl]azetidine-3-carboxylic acid (CAS 1350989-07-9)
- 1-(3-Bromo-2,2-dimethylpropyl)-4-ethylbenzene (CAS 1483261-90-0)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com