Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylate CAS 67286-71-9
| CAS No. | 67286-71-9 |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylate (CAS 67286-71-9), molecular formula C10H14N2O2 and molecular weight 194.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylate (C10H14N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 2-(8-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)acetic acid (CAS 1267316-63-1)
- Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-6-carboxylate (CAS 139183-96-3)
- Ethyl 5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-5-carboxylate (CAS 873785-71-8)
- 2-(3-Ethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl)ethanamine (CAS 1539241-82-1)
- 5-Oxo-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidine-7-carbohydrazide (CAS 1008466-88-3)
- Ethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylate (CAS 1286753-85-2)
- Ethyl 1,2,3,4-tetrahydroimidazo[1,5-a]pyrimidine-8-carboxylate (CAS 2090110-55-5)
- Ethyl 5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-2-carboxylate (CAS 91476-82-3)
Recommended Standards
- Ethyl 4-propylpyrimidine-5-carboxylate (CAS 887408-28-8)
- ETHYL 4-METHOXY-2-METHYLBENZOATE (CAS 56427-62-4)
- Ethyl 5-Amino-4,6-dimethylnicotinate (CAS 90873-35-1)
- Ethyl 4-isopropylpyrimidine-5-carboxylate (CAS 887408-29-9)
- 6-Ethyl-2-(1H-pyrrol-1-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid (CAS 1707370-42-0)
- 5-((4-Formyl-2-methoxyphenoxy)methyl)furan-2-carboxylic acid (CAS 827011-73-4)
- 2-methyl-1,3-benzoxazole-7-carbaldehyde (CAS 1500924-89-9)
- H-Tyr-NH2 · HCl (CAS 53559-18-5)
- 7-Methyl-2-phenylquinazolin-4(3H)-one (CAS 158832-76-9)
- 2-(2-(((tert-Butoxycarbonyl)amino)methyl)-1H-benzo[d]imidazol-1-yl)acetic acid (CAS 1207044-25-4)
- 6-Bromo-1H-pyrrolo[3,2-b]pyridin-3-amine hydrochloride (CAS 1260381-81-4)
- 7-Isobutyl-1,3-dimethyl-8-(propylamino)-3,7-dihydro-1H-purine-2,6-dione (CAS 941993-70-0)
- 4-(Difluoromethyl)-2,6-difluoronicotinic acid (CAS 1805241-86-4)
- Des-Phe22-Tirzepatide (CAS CATO-CPTD788951)
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