2-Bromo-5-methylbenzene-1,4-diol CAS 67289-05-8
| CAS No. | 67289-05-8 |
| Molecular Formula | C7H7BrO2 |
| Molecular Weight | 203.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-methylbenzene-1,4-diol.
2-Bromo-5-methylbenzene-1,4-diol (CAS 67289-05-8) is a high-purity analytical reference standard with the molecular formula C7H7BrO2 and a molecular weight of 203.03 g/mol.
The molecular framework of 2-Bromo-5-methylbenzene-1,4-diol (C7H7BrO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-5-methylbenzene-1,4-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BrO2 |
| Molecular Weight | 203.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Br-containing |
Related Bromo Standards
- 3-Bromo-5-hydroxybenzyl Alcohol (CAS 1020336-51-9)
- 3-Bromo-5-methylbenzene-1,2-diol (CAS 117654-19-0)
- 2-Bromo-1-(4-methylfuran-2-yl)ethanone (CAS 133674-82-5)
- 2-Bromo-3-methoxyphenol (CAS 135999-16-5)
- 4-Bromo-2-methylbenzene-1,3-diol (CAS 139553-46-1)
- 2-Bromo-1-(5-methylfuran-2-yl)ethanone (CAS 1634-53-3)
- 5-Bromo-2-(hydroxymethyl)phenol (CAS 170434-11-4)
- 2-Bromo-4-methoxyphenol (CAS 17332-11-5)
Recommended Standards
- 2-Bromo-5-methoxyphenol, 97% (CAS 63604-94-4)
- 2-Bromo-6-(hydroxymethyl)phenol (CAS 28165-46-0)
- 2-Bromo-4-(hydroxymethyl)phenol (CAS 29922-56-3)
- 2-Bromo-6-methoxyphenol (CAS 28165-49-3)
- (3-Bromophenyl)(2-methylpyridin-4-yl)methanone (CAS 1187169-54-5)
- 3-Methyl-N-(thiophen-2-ylmethyl)pentan-2-amine (CAS 1042528-42-6)
- n-(3-Bromophenyl)-3-(1h-pyrazol-1-yl)propanamide (CAS 895250-84-7)
- 3-(Benzenesulfonyl)quinolin-2-amine (CAS 861386-01-8)
- 2-Chloro-N-ethylbenzamide (CAS 66896-65-9)
- Rel-calcium (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylate (CAS 5793-87-3)
- (4-Methoxy-3-propoxyphenyl)boronic acid (CAS 150145-31-6)
- 2-((2-Oxopropyl)thio)-3-phenylquinazolin-4(3H)-one (CAS 18741-31-6)
- 1,2,4,5-Tetrafluoro-3,6-bis(2,2,2-trifluoroethoxy)benzene (CAS 6715-31-7)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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