1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-{3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}piperidine-4-carboxamide CAS 672949-06-3
| CAS No. | 672949-06-3 |
| Molecular Formula | C24H20Cl3F3N4O3 |
| Molecular Weight | 575.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-{3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}piperidine-4-carboxamide.
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-{3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}piperidine-4-carboxamide (CAS 672949-06-3), molecular formula C24H20Cl3F3N4O3 and molecular weight 575.79 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-{3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}piperidine-4-carboxamide (C24H20Cl3F3N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-{3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}piperidine-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H20Cl3F3N4O3 |
| Molecular Weight | 575.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- N2-[4-chloro-2-({[3-chloro-5-(trifluoromethyl)-2-pyridyl]carbonyl}amino)-5-fluorophenyl]-3-chloro-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 247060-60-2)
- ((2-Butyl-4-chloro-1-((2`-(1-nitroso-1H-tetrazol-5-yl)-[1,1`-biphenyl]-4-yl)methyl)-1H-imidazole-5-yl)methonol) (CAS CATO-C3D-26203)
- 1-(3-Chloro-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-2-yl)urea (CAS 338407-21-9)
- N'-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N'-methyl-2-oxoacetohydrazide (CAS 338409-91-9)
- 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-2-yl}-N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)acetamide (CAS 337920-35-1)
- 5-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)-1-(4-chlorophenyl)-3-(4-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 321534-68-3)
- 3-(5-Chloro-2-hydroxyphenyl)-5-isopropylimidazolidine-2,4-dione (CAS 55345-44-3)
- (E)-2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}-N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)ethene-1-sulfonamide (CAS 478246-23-0)
Recommended Standards
- Alfacalcidol EP Impurity C (CAS 82266-85-1)
- 1,1'-((2,2,2-Trichloroethane-1,1-diyl)bis(azanediyl))bis(anthracene-9,10-dione) (CAS 89734-98-5)
- 24,25-Dihydroglycofusidic Acid (CAS 53163-88-5)
- N-(4-Dodecyl-3-methoxyphenazin-2-yl)dodecanamide (CAS 63124-92-5)
- 2,3-Dimethyl-5-nitro-2,3-dihydrophthalazine-1,4-dione (CAS 858243-19-3)
- ethyl 2-bromo-2-(2-bromo-5-methyl-1,3-thiazol-4-yl)acetate (CAS 1955548-41-0)
- Mazdutide (CAS CATO-C4X-35011)
- Methyl (3R,4S)-3-hydroxytetrahydro-2H-pyran-4-carboxylate (CAS 1904088-44-3)
- 5-(1,3-Dioxolan-2-yl)-2-methylbenzofuran (CAS 648449-70-1)
- 4-Ethyl-3-isobutyl-1h-pyrazol-5-amine (CAS 1187561-77-8)
- Ethyl[(2-methylphenyl)methyl]amine (CAS 62924-60-1)
- 4-Cyclopropoxy-2-isopropylpyridin-3-amine (CAS 1243323-25-2)
- Tert-butyl 4-((tert-butoxycarbonyl)amino)-4-(3-((2-oxo-2-propoxyethyl)amino)oxetan-3-yl)butanoate (CAS 2201584-13-4)
- D-[Ser]8-Semaglutide (CAS CATO-C4X-2226207)
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