7-(Chlorodifluoromethyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidine CAS 672949-51-8
| CAS No. | 672949-51-8 |
| Molecular Formula | C18H15ClF2N4S |
| Molecular Weight | 392.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-(Chlorodifluoromethyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidine.
7-(Chlorodifluoromethyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidine (CAS 672949-51-8) is a high-purity analytical reference standard with the molecular formula C18H15ClF2N4S and a molecular weight of 392.85 g/mol.
Based on its molecular formula C18H15ClF2N4S, 7-(Chlorodifluoromethyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 392.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-(Chlorodifluoromethyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-methylpyrazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15ClF2N4S |
| Molecular Weight | 392.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorodifluoromethyl Standards
- (5-(Chlorodifluoromethyl)-2,3-dihydro-1H-1,4-diazepin-1-yl)(3-(2-chlorophenyl)-5-methylisoxazol-4-yl)methanone (CAS 444151-89-7)
- 3-(Chlorodifluoromethyl)-6-((5-(trifluoromethyl)pyridin-2-yl)thio)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 477871-70-8)
- 7-(Chlorodifluoromethyl)-5-methyl-2-(4-phenylpiperazin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 691873-03-7)
- 2-((3-(Chlorodifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)benzo[d]thiazole (CAS 477871-64-0)
- 3-(Chlorodifluoromethyl)-6-(2,4-dichlorophenyl)-7h-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CAS 832739-69-2)
- 4-[7-(Chlorodifluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidin-2-yl]-1-methyl-5-(trifluoromethyl)-1H-pyrazole (CAS 956165-30-3)
- 4-Benzyl-2-(4-(chlorodifluoromethyl)-6-methylpyrimidin-2-yl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 866137-92-0)
- 5-(Chlorodifluoromethyl)-1-(mesitylsulfonyl)-2,3-dihydro-1H-1,4-diazepine (CAS 439096-53-4)
Recommended Standards
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-(4-fluorobenzyl)-1H-pyrazole (CAS 956755-21-8)
- 2-((4-(((4-Chlorophenyl)methyl)sulfonamido)but-2-yn-1-yl)oxy)benzamide (CAS 1448031-19-3)
- 2-((4-Chlorophenyl)sulfinyl)-1,1-bis(4-fluorophenyl)ethanol (CAS 303152-28-5)
- N-(4-(3-((4-Chlorophenyl)sulfonyl)azetidine-1-carbonyl)phenyl)acetamide (CAS 1448136-62-6)
- (2-Amino-phenyl)-(2-fluoro-phenyl)-methanone (2-Aminophenyl)(2-fluorophenyl)methanone 1581-13-1 A3482 (CAS 1581-13-1)
- 3,5-Dichloropicolinimidamide hydrochloride (CAS 1245806-97-6)
- Ethyl 2-amino-4-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 95211-67-9)
- (3-Fluoro-pyridin-4-yl)-oxo-acetic acid methyl ester (CAS 2149202-25-3)
- 3-Fluoro-5-cyclopropylpyridine (CAS 1414870-74-8)
- N-(Prop-2-yn-1-yl)nicotinamide (CAS 18327-30-5)
- 6638-64-8 3-Nitro-6H-dibenzo(b,d)pyran-6-one 6H-Dibenzo(b,d)pyran-6-one, 3-nitro- 2-Biphenylcarboxylic acid, 2'-hydroxy-4'-nitro-, delta-lactone CCRIS 7714 (CAS 6638-64-8)
- 2-(4-Chlorobenzoyl)benzofuran-5-carbaldehyde (CAS 300664-78-2)
- 4-(1,2-Dimethyl-propyl)-pyridine (CAS 27876-22-8)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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