(E)-[1-(4-Fluorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethylidene](methoxy)amine CAS 672951-77-8
| CAS No. | 672951-77-8 |
| Molecular Formula | C19H21F2N3O |
| Molecular Weight | 345.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-[1-(4-Fluorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethylidene](methoxy)amine.
(E)-[1-(4-Fluorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethylidene](methoxy)amine (CAS 672951-77-8) is a high-purity analytical reference standard with the molecular formula C19H21F2N3O and a molecular weight of 345.39 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (E)-[1-(4-Fluorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethylidene](methoxy)amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 345.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-[1-(4-Fluorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]ethylidene](methoxy)amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21F2N3O |
| Molecular Weight | 345.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related E Standards
- 1-[4-(4-Fluorophenyl)-2-thiazolyl]-3,5-dimethyl-1H-pyrazole-4-propanoic Acid (CAS 1172940-17-8)
- Bis(3-fluorophenyl)methyl 1-methylpiperidine-4-carboxylate (CAS 1404055-13-5)
- 7-(((4-Fluorophenyl)amino)(pyridin-4-yl)methyl)quinolin-8-ol (CAS 308298-23-9)
- 7-((3-Fluorophenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol (CAS 315698-37-4)
- 5-(4-Fluorophenyl)-2-{[(2-piperazin-1-ylethyl)-amino]methylene}cyclohexane-1,3-dione (CAS 432532-88-2)
- N-(4-(4-Fluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide (CAS 721909-07-5)
- 202859-11-8 4-(4-Fluorophenyl)-5-(hydroxymethyl)-2,6-bis(1-methylethyl)-3-pyridinecarboxylic Acid Methyl Ester Methyl 2,6-Diisopropyl-4-(4-fluorophenyl)-5-hydroxymethyl-pyridine-3-carboxy-late (CAS 202859-11-8)
- 4-(5-(4-Fluorophenyl)-4-formyl-1H-pyrazol-1-yl)benzenesulfonamide (CAS 676233-44-6)
Recommended Standards
- (9H-Fluoren-9-yl)methyl benzyloxycarbamate (CAS 566200-23-5)
- (E)-{[4-(benzyloxy)phenyl]methylidene}amino 4-methylbenzoate (CAS 551931-09-0)
- (9H-Fluoren-9-yl)methyl benzyl(hydroxy)carbamate (CAS 198411-59-5)
- (E)-2-(4-oxo-5-((5-phenylfuran-2-yl)methylene)-2-thioxothiazolidin-3-yl)acetic acid (CAS 294657-85-5)
- 2,4-Diaminoquinazoline-6-carbonitrile (CAS 18917-68-5)
- Quinidine N-Oxide (CAS 70116-00-6)
- 1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-dione (CAS 149579-07-7)
- 4-Chloro-6-iodopyridine-2-sulfonyl chloride (CAS 1393533-88-4)
- 2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 332948-44-4)
- 4,4-Dimethyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (CAS 78103-80-7)
- tributyl-(6-ethoxypyrazin-2-yl)stannane (CAS 1224436-45-6)
- 4-Chloro-5-hydroxy-2-isopropylpyridazin-3(2H)-one (CAS 64178-62-7)
- (E)-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)piperazine-1-carboxamide (CAS 339029-24-2)
- Exenatide (CAS 141758-74-9（free base）)
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