2-{3,3,3-trifluoro-2-[(trimethylsilyl)oxy]propyl}-1,2,3,4-tetrahydroisoquinoline CAS 672952-09-9
| CAS No. | 672952-09-9 |
| Molecular Formula | C15H22F3NOSi |
| Molecular Weight | 317.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-{3,3,3-trifluoro-2-[(trimethylsilyl)oxy]propyl}-1,2,3,4-tetrahydroisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-{3,3,3-trifluoro-2-[(trimethylsilyl)oxy]propyl}-1,2,3,4-tetrahydroisoquinoline (CAS 672952-09-9) is a high-purity analytical reference standard with the molecular formula C15H22F3NOSi and a molecular weight of 317.42 g/mol.
The molecular framework of 2-{3,3,3-trifluoro-2-[(trimethylsilyl)oxy]propyl}-1,2,3,4-tetrahydroisoquinoline (C15H22F3NOSi) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H22F3NOSi |
| Molecular Weight | 317.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 3-(Tritylamino)propan-1-ol (CAS 89448-83-9)
- N-(4-((4-fluorophenyl)thio)phenyl)acetamide (CAS 90309-32-3)
- Bis(2-carboxyphenyl) succinate (CAS 578-19-8)
- N-(tert-Butyl)hydroxylamine Hydrochloride (CAS 57497-39-9)
- N-(azetidin-3-yl)-N-methylcyclobutanecarboxamide (CAS 1496790-15-8)
- 3-Isopentyl-2-thioxoimidazolidin-4-one (CAS 900006-23-7)
- 5-(3-Chlorophenyl)-4h-1,2,4-triazole-3-carboxylic acid (CAS 944897-45-4)
- Bazedoxifene Impurity E (CAS 857594-21-9)
- (1-(5-Bromopyridin-2-yl)piperidin-4-yl)methanamine hydrochloride (CAS 1417794-58-1)
- (S)-2-Amino-3-cyclopropylpropan-1-ol (CAS 1038393-52-0)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com