2-Amino-4-methylthiazole-5-carbonitrile CAS 67322-84-3
| CAS No. | 67322-84-3 |
| Molecular Formula | C5H5N3S |
| Molecular Weight | 139.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Amino-4-methylthiazole-5-carbonitrile (CAS 67322-84-3) is a high-purity analytical reference standard with the molecular formula C5H5N3S and a molecular weight of 139.18 g/mol.
2-Amino-4-methylthiazole-5-carbonitrile (C5H5N3S) contains a nitrile group, sulfur-containing functionality. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5N3S |
| Molecular Weight | 139.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-5-methylthiazole-4-carbonitrile (CAS 1379308-53-8)
- 2-(Amino(methylthio)methylene)malononitrile (CAS 18071-20-0)
- 4-Amino-3-methyl-isothiazole-5-carbonitrile (CAS 4592-55-6)
- 5-Amino-2-methylthiazole-4-carbonitrile (CAS 31785-16-7)
- 5-Amino-3-methylisothiazole-4-carbonitrile (CAS 41808-35-9)
- 3-amino-1-ethynylcyclohexan-1-ol (CAS 1516219-68-3)
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- 3-Amino-2-methyl-benzyl-d (CAS 57414-76-3)
Recommended Standards
- 2-[(Methylamino)(sulfanyl)methylidene]propanedinitrile (CAS 32827-61-5)
- 2-Isothiocyanato-1-methyl-1H-imidazole (CAS 947312-04-1)
- 2-(Aminomethyl)thiazole-5-carbonitrile (CAS 749834-79-5)
- 2-(Aminomethyl)thiazole-4-carbonitrile (CAS 302341-70-4)
- 3,6-Dichloro-2-(difluoromethoxy)benzyl bromide (CAS 1806328-29-9)
- N-methyl-N-(pyridin-4-ylmethyl)nitrous amide (CAS 6335-95-1)
- 3-Cyano-N-((tetrahydrofuran-2-yl)methyl)benzamide (CAS 1008386-47-7)
- 3-methoxy-1-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylmethyl)-1H-pyrazol-4-amine,HCl (CAS 1431965-23-9)
- 2-Butenedioic acid (2Z)-, 1,4-dibutyl ester, polymer with ethenyl acetate and 2-methyl-2,4-pentanediol (CAS 67939-18-8)
- Diphenyl (1-amino-3-methylbutyl)phosphonate hydrochloride (CAS 1170612-38-0)
- Isopropyl 2-((5-(((4-chlorophenyl)amino)methyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetate (CAS 482652-69-7)
- n-(1-(2,4-Difluorophenyl)ethyl)propan-2-amine (CAS 1021091-79-1)
- 1-Cyclohexyl-3-(2-(thiophene-2-carbonyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)urea (CAS 1207023-67-3)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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