2-[2-(bromomethyl)-4-fluoro-phenyl]-5,5-dimethyl-1,3,2-dioxaborinane CAS 673456-16-1

Purity 97%+In StockPharmaceutical Standards
CAS No.673456-16-1
Molecular FormulaC12H15BBrFO2
Molecular Weight300.96 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[2-(bromomethyl)-4-fluoro-phenyl]-5,5-dimethyl-1,3,2-dioxaborinane CAS 673456-16-1 chemical structure

Description

As a certified reference material (CRM), 2-[2-(bromomethyl)-4-fluoro-phenyl]-5,5-dimethyl-1,3,2-dioxaborinane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies 2-[2-(bromomethyl)-4-fluoro-phenyl]-5,5-dimethyl-1,3,2-dioxaborinane (CAS 673456-16-1), a certified reference material (molecular formula C12H15BBrFO2, MW 300.96 g/mol) for analytical method development and quality control.

The molecular framework of 2-[2-(bromomethyl)-4-fluoro-phenyl]-5,5-dimethyl-1,3,2-dioxaborinane (C12H15BBrFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC12H15BBrFO2
Molecular Weight300.96 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Br-containing

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