2-Acrylamido-2-hydroxyacetic acid CAS 6737-24-2
| CAS No. | 6737-24-2 |
| Molecular Formula | C5H7NO4 |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Acrylamido-2-hydroxyacetic acid is closely related to a carbohydrate-derived structure, an amide group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Acrylamido-2-hydroxyacetic acid (CAS 6737-24-2), a certified reference material (molecular formula C5H7NO4, MW 145.11 g/mol) for analytical method development and quality control.
Structurally, 2-Acrylamido-2-hydroxyacetic acid (C5H7NO4) contains a carbohydrate-derived structure, an amide group. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 145.11 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Acrylamido-2-hydroxyacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7NO4 |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Acrylamido Standards
- 3-Acrylamido-3-methylbutanoic acid (CAS 38486-53-2)
- 2-Acrylamido-2-ethylbutanoic acid (CAS 111818-56-5)
- (S)-6-Acrylamido-2-aminohexanoic acid (CAS 48065-82-3)
- Butyl 2-acrylamido-2-hydroxyacetate (CAS 89995-71-1)
- 2-Acrylamido-2-phenylacetic acid (CAS 173947-32-5)
- 2-Acrylamido-2-methylpropanesulfonic Acid (CAS 15214-89-8)
- 2-Acrylamido-2-((ethoxycarbonyl)amino)acetic acid (CAS 65954-91-8)
- (5-Acrylamido-2-(aminomethyl)phenyl)boronic acid (CAS 1217500-77-0)
Recommended Standards
- 2-[(4S)-2-Oxo-1,3-oxazolidin-4-yl]acetic acid (CAS 749205-02-5)
- 2-Amino-3,4-difluorophenol (CAS 865106-45-2)
- 2,6-Difluoropyridine-3,4-diamine (CAS 60186-25-6)
- 3,5-Difluoro-2-hydrazinylpyridine (CAS 851179-06-1)
- N-(4-Chlorophenyl)-[1,1'-biphenyl]-4-carboxamide (CAS 312759-00-5)
- (3-Allylphenyl)(butyl)sulfane (CAS 1379346-08-3)
- Sodium 3-bromopyridine-2-sulfinate (CAS 2137725-62-1)
- 4-Methoxy-3-[(3-methylphenoxy)methyl]benzoic acid (CAS 438220-78-1)
- tert-Butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate (CAS 286946-98-3)
- 3-(Pyrazolo[1,5-a][1,2,4]triazolo[3,4-c]pyrazin-3-yl)propanoic acid (CAS 1707594-83-9)
- Guaiacol Carbonate (CAS 553-17-3)
- 2-Cyclopropyl-6-(pyridin-4-yl)pyrimidin-4-amine (CAS 1159814-91-1)
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2H-1,2,3-triazole (CAS 1312479-18-7)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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