ethyl 2-cyano-2-methyl-2-[(trimethylsilyl)oxy]acetate CAS 67405-85-0
| CAS No. | 67405-85-0 |
| Molecular Formula | C9H17NO3Si |
| Molecular Weight | 215.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
ethyl 2-cyano-2-methyl-2-[(trimethylsilyl)oxy]acetate (CAS 67405-85-0) is a high-purity analytical reference standard with the molecular formula C9H17NO3Si and a molecular weight of 215.32 g/mol.
ethyl 2-cyano-2-methyl-2-[(trimethylsilyl)oxy]acetate (C9H17NO3Si) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H17NO3Si |
| Molecular Weight | 215.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 1 |
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