6-chloro-3-methyl-[1,2,4]triazolo[3,4-a]phthalazine CAS 67458-38-2
| CAS No. | 67458-38-2 |
| Molecular Formula | C10H19ClN4 |
| Molecular Weight | 230.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-chloro-3-methyl-[1,2,4]triazolo[3,4-a]phthalazine is closely related to a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-chloro-3-methyl-[1,2,4]triazolo[3,4-a]phthalazine (CAS 67458-38-2) is a high-purity analytical reference standard with the molecular formula C10H19ClN4 and a molecular weight of 230.74 g/mol.
The molecular framework of 6-chloro-3-methyl-[1,2,4]triazolo[3,4-a]phthalazine (C10H19ClN4) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-chloro-3-methyl-[1,2,4]triazolo[3,4-a]phthalazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H19ClN4 |
| Molecular Weight | 230.74 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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