3-(4-Chlorobenzyl)pyrrolidin-3-ol hydrochloride CAS 67466-33-5
| CAS No. | 67466-33-5 |
| Molecular Formula | C11H14ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(4-Chlorobenzyl)pyrrolidin-3-ol hydrochloride (CAS 67466-33-5), molecular formula C11H14ClNOHCl and molecular weight 248.15 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-Chlorobenzyl)pyrrolidin-3-ol hydrochloride (C11H14ClNOHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-(4-Chlorobenzyl)pyrrolidin-3-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO HCl |
| Molecular Weight | 248.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzyl Standards
- 1-(4-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001510-38-8)
- 1-(3-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001566-82-0)
- 1-(3-Chlorobenzyl)-1H-pyrazol-4-amine (CAS 1002033-41-1)
- 3-(2-Chlorobenzyl)pyrrolidine (CAS 1003561-98-5)
- 1-(3-Chlorobenzyl)-4-isothiocyanato-1h-pyrazole (CAS 1004193-35-4)
- 1-(3-Chlorobenzyl)-5-methyl-1,2-dihydro-3h-pyrazol-3-imine (CAS 1004643-48-4)
- 1-(4-Chlorobenzyl)-2-oxo-N-(3-phenylpropyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 1005291-55-3)
- 1-(2-Chlorobenzyl)-5-methyl-3,4-dinitro-1h-pyrazole (CAS 1005669-24-8)
Recommended Standards
- Melamine diamide-<SUP>13</SUP>C<SUB>3</SUB> (CAS 1173018-57-9)
- N-(4-Chlorophenyl)-2-oxooxazolidine-3-sulfonamide (CAS 848937-72-4)
- Tert-butyl (S)-4-(1-amino-2-methoxy-2-oxoethyl)piperidine-1-carboxylate (CAS 368866-12-0)
- 5-Oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid (CAS 339020-61-0)
- Ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate (CAS 672323-07-8)
- 2,3-Dichloro-6-hydroxybenzoic acid (CAS 1806282-06-3)
- 5-Methyl-4-nitro-2-pyridinamine (CAS 895520-03-3)
- 2-(4-Chlorophenyl)-5-(1,2,3,4-tetrahydropyrazin-2-yl)-4H-1,3-thiazin-4-one (CAS 89442-14-8)
- Ruxolitinib Impurity 110 (CAS CATO-C4X-2058110)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
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