2,6-Difluoropyrimidin-4-amine CAS 675-12-7
| CAS No. | 675-12-7 |
| Molecular Formula | C4H3F2N3 |
| Molecular Weight | 131.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 131.08 g/mol gives 2,6-Difluoropyrimidin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,6-Difluoropyrimidin-4-amine (CAS 675-12-7), molecular formula C4H3F2N3 and molecular weight 131.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,6-Difluoropyrimidin-4-amine (C4H3F2N3) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,6-Difluoropyrimidin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H3F2N3 |
| Molecular Weight | 131.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoropyrimidin Standards
- 5,6-Difluoropyrimidin-4-amine (CAS 1403948-10-6)
- 4,6-Difluoropyrimidin-5-amine (CAS 669-80-7)
- 2,6-Difluoropyrimidin-4(3H)-one (CAS 256234-39-6)
- 1-(2,4-Difluoropyrimidin-5-yl)ethanol (CAS 161123-97-3)
- 4-(4,6-Difluoropyrimidin-2-yl)morpholine (CAS 189003-02-9)
- (R)-3-(2,5-Difluoropyrimidin-4-yl)-4-(fluoromethyl)oxazolidin-2-one (CAS 1628810-38-7)
Recommended Standards
- 2,6-Difluoropyridin-3-ol (CAS 209328-85-8)
- 2-Amino-4,6-difluoropyrimidine (CAS 675-11-6)
- 2,4-Difluoropyridine 1-Oxide (CAS 303154-04-3)
- 3,5-Difluoro-1H-pyridin-2-one (CAS 914482-23-8)
- 213843-90-4 (3aR,8aR)-N,N,2,2-Tetramethyl-4,4,8,8-tetraphenyltetrahydro-2H,6H-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-amine DTXSID40456805 (CAS 213843-90-4)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-cyclohexylthiazol-4-yl)boronate (CAS 2223042-04-2)
- Ethyl 2-(2,4,5-trioxoimidazolidin-1-yl)acetate (CAS 89694-35-9)
- 2-(4-(4-Bromo-2-fluorobenzyl)piperazin-1-yl)acetic acid (CAS 1155159-65-1)
- 4,9-Dibromo-2,7-bis(2-butyloctyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone (CAS 1614253-96-1)
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