7,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one CAS 675132-40-8
| CAS No. | 675132-40-8 |
| Molecular Formula | C10H8F2O |
| Molecular Weight | 182.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 7,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 7,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one (CAS 675132-40-8), a certified reference material (molecular formula C10H8F2O, MW 182.17 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F2O |
| Molecular Weight | 182.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Difluoro Standards
- Ethyl 2,2-difluoro-3-hydroxypentanoate (CAS 1092693-68-9)
- 5,7-Difluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 110931-79-8)
- 2,2-Difluoro-3-hydroxy-5-methylhexanoic acid (CAS 1248009-70-2)
- 2,2-Difluoro-3-hydroxy-4-methylhexanoic acid (CAS 1249092-91-8)
- 2,2-Difluoro-3-hydroxy-3,4-dimethylpentanoic acid (CAS 1249974-94-4)
- 7,8-Difluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1273662-15-9)
- 4,6-Difluoro-1,3-dimethyl-1H-indazole (CAS 1329167-03-4)
- (5,6-Difluoro-1H-indol-3-yl)methanamine (CAS 1360891-58-2)
Recommended Standards
- 6,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one (CAS 843644-23-5)
- cis-endo-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid (CAS 3853-88-1)
- 6,7-difluoro-2-tetralone (CAS 552321-02-5)
- Cyclobuta[b]naphthalene-1,2-dione (CAS 41634-34-8)
- 2-(2-hydroxyphenyl)-2-methoxyacetic acid (CAS 75335-12-5)
- 2-(2-Methyl-1H-1,3-benzodiazol-1-yl)acetohydrazide (CAS 97420-40-1)
- 7-chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridine hydrochloride (CAS 917918-83-3)
- 3-(4-Aminopiperidin-1-yl)pyrrolidine-2,5-dione dihydrochloride (CAS 1394632-97-3)
- Vilanterol Impurity 16 (CAS CATO-C4X-193516)
- 5-Acetyl-2,3-Dihydro-1-Benzofuran (CAS 90843-31-5)
- (2E)-3-(4-Nitrophenyl)-2-phenylacrylic acid (CAS 19319-30-3)
- Ethyl 4-((4-(2-isonicotinoylhydrazineyl)-6-(p-tolylamino)-1,3,5-triazin-2-yl)amino)benzoate (CAS 84523-94-4)
- Norfloxacin Impurity 23 (CAS CATO-C4X-146823)
- Insulin Glargine (CAS 160337-95-1)
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