2-(Hydroxymethyl)-5-(trifluoromethyl)benzimidazole CAS 6758-34-5
| CAS No. | 6758-34-5 |
| Molecular Formula | C9H7F3N2O |
| Molecular Weight | 216.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Hydroxymethyl)-5-(trifluoromethyl)benzimidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(Hydroxymethyl)-5-(trifluoromethyl)benzimidazole (CAS 6758-34-5), a certified reference material (molecular formula C9H7F3N2O, MW 216.16 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Hydroxymethyl)-5-(trifluoromethyl)benzimidazole (C9H7F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7F3N2O |
| Molecular Weight | 216.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Hydroxymethyl Standards
- 2-(Hydroxymethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one (CAS 61645-36-1)
- 3'-(Hydroxymethyl)-[1,1'-biphenyl]-3,4-diol (CAS 1349715-76-9)
- 4'-(Hydroxymethyl)-[1,1'-biphenyl]-3,4-diol (CAS 1349718-88-2)
- Methyl 7-(hydroxymethyl)-2-naphthoate (CAS 162514-08-1)
- 8-(Hydroxymethyl)-1,4-dioxaspiro[4.5]decane-8-carboxylic acid (CAS 1818868-43-7)
- 4-(3-(Hydroxymethyl)phenoxy)phenol (CAS 63987-19-9)
- Methyl 6-(hydroxymethyl)-2-naphthoate (CAS 55343-77-6)
- 2-(Hydroxymethyl)-3,6,7,8-tetrahydro-4H-cyclopenta[g]quinazolin-4-one (CAS 501131-95-9)
Recommended Standards
- 2-(Difluoromethyl)-5-fluoro-6-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 2149590-61-2)
- 2-(Trifluoromethyl)-5,8-dihydroquinazolin-7(6H)-one (CAS 944896-00-8)
- 2-(Aminomethyl)-6-(trifluoromethyl)benzo[d]oxazole (CAS 944907-51-1)
- 2-(Trifluoromethyl)-7,8-dihydroquinazolin-6(5H)-one (CAS 944902-21-0)
- 3-Chloro-2-(2-ethyl-1-piperidinyl)-5-(trifluoromethyl)pyridine (CAS 1219961-17-7)
- 8-((5,6,7,8-Tetrahydronaphthalen-2-yl)sulfonyl)-8-azabicyclo[3.2.1]oct-2-ene (CAS 1798047-09-2)
- 1,10-Phenanthroline-4,7-diol hydrochloride (CAS 61626-11-7)
- (R)-Indobufen (CAS 131484-83-8)
- Ethyl 5-acetyl-2-oxo-2,3-dihydropyrimidine-4-carboxylate (CAS 62328-18-1)
- Emedastine EP Impurity C (CAS 122423-32-9(Free Base))
- 6-(Difluoromethoxy)-1-methyl-1H-indazol-3-amine (CAS 1192813-39-0)
- 2-((Pyridin-4-ylmethyl)amino)butan-1-ol hydrochloride (CAS 1158735-57-9)
- Minocycline (CAS 10118-90-8)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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