5-(4-Methoxyphenyl)quinolin-8-ol CAS 675880-72-5
| CAS No. | 675880-72-5 |
| Molecular Formula | C16H13NO2 |
| Molecular Weight | 251.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 5-(4-Methoxyphenyl)quinolin-8-ol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-(4-Methoxyphenyl)quinolin-8-ol (CAS 675880-72-5), molecular formula C16H13NO2 and molecular weight 251.28 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13NO2 |
| Molecular Weight | 251.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-(4-Methoxyphenyl)-3-phenylisoxazole (CAS 3672-51-3)
- 5-(5-AMinopentyl)-5-(2-furyl)-2,4-imidazolidinedione (CAS 878788-02-4)
- 5-(4-Methoxyphenyl)-2-phenyloxazole (CAS 62921-42-0)
- 5-(Phenoxymethyl)-3-phenyl-1,2-oxazole (CAS 35121-46-1)
- 2-(3,4-Dimethoxy-benzyl)-piperidine (CAS 102458-70-8)
- 1-Fluoro-4-(iodomethyl)benzene (CAS 3831-29-6)
- 3-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 1620575-00-9)
- 2-(Methylamino)butanoic acid hydrochloride (CAS 1214138-93-8)
- 1-(3-Chlorophenyl)-5-ethyl-1h-pyrazol-4-amine (CAS 1521422-25-2)
- tert-Butyl 3-formyl-1h-pyrrolo[3,2-c]pyridine-1-carboxylate (CAS 877060-55-4)
- 7-Chloro-2,3-dihydrobenzofuran (CAS 1174005-71-0)
- (2-(Azetidin-1-ylmethyl)phenyl)(3-chloro-5-fluorophenyl)methanone (CAS 898755-17-4)
- 1-(4-Chloro-7-methoxyquinolin-2-yl)-3-phenylurea (CAS 196875-43-1)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
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